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Description
  • The review describes cerebral detoriaration on vascular grounds in 3 levels. Occlusions of big vessels with a single major infarct, middle calibre vasculopathy with multiple lacunes and finally microangiopathy causing leukoaraiosis. Changes in the vessel wall, in cerebral blood flow velocity, the territorial and interterritorial rules for the location of malacia or lacunes are reviewed using neuroradiologic aspect revealed by ultrasound, by CT and MRI. Alteration in diffusion and their measurements by MRI are discussed in regard to ultrastructural reactions to ischaemia. Thresholds for tissue deterioration are shown in association with ATP depletion and with pathologic compounds in the interstitium.
  • The review describes cerebral detoriaration on vascular grounds in 3 levels. Occlusions of big vessels with a single major infarct, middle calibre vasculopathy with multiple lacunes and finally microangiopathy causing leukoaraiosis. Changes in the vessel wall, in cerebral blood flow velocity, the territorial and interterritorial rules for the location of malacia or lacunes are reviewed using neuroradiologic aspect revealed by ultrasound, by CT and MRI. Alteration in diffusion and their measurements by MRI are discussed in regard to ultrastructural reactions to ischaemia. Thresholds for tissue deterioration are shown in association with ATP depletion and with pathologic compounds in the interstitium. (en)
  • Přehled popisuje mozkovou deterioraci z vaskulárních příčin na třech úrovních. Uzávěry velkých tepen s jediným velkým infarktem, vaskulopatie tepen středního kalibru s mnohotnými lakunami a nakonec mikroangiopatii, způsobující leukoaraiózu. Jsou zpřehledněny změny v cévní stěni, v rychlosti krevního toku, pravidla pro teritoriální a interteritoriální lokalizaci malácií nebo lakun, vše se zřetelem k neuroradiologickým projevům, získaným ultrazvukem, CT a MRI. Diskutovány jsou alterace difúze a jejího MR měření ve vztahu k ultrastrukturáním dopadům při ischemii. Jsou demonstrovány prahy pro tkáňovou deterioraci ve vztahu k depleci ATP a k patologickým sloučeninám v intersticiu. (cs)
Title
  • Cerebral microangiopathy in the mosaic of new discoveries
  • Mozková mikroangiopatie v mozaice nových objevů (cs)
  • Cerebral microangiopathy in the mosaic of new discoveries (en)
skos:prefLabel
  • Cerebral microangiopathy in the mosaic of new discoveries
  • Mozková mikroangiopatie v mozaice nových objevů (cs)
  • Cerebral microangiopathy in the mosaic of new discoveries (en)
skos:notation
  • RIV/00216208:11120/05:00009505!RIV06-MSM-11120___
http://linked.open.../vavai/riv/strany
  • 7;12
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM 111200004)
http://linked.open...iv/cisloPeriodika
  • 1-2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 514665
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/05:00009505
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Cerebral; microangiopathy; mosaic; discoveries (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [7570DE84AC73]
http://linked.open...i/riv/nazevZdroje
  • Journal of the Neurological Sciences
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 229-230
http://linked.open...iv/tvurceVysledku
  • Kalvach, Pavel
http://linked.open...n/vavai/riv/zamer
issn
  • 0022-510X
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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