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Description
  • Studovali jsme metabolismus glukózy u septikých pacientů při hyperinzulinovém clampu a porovnávali jsme různé úrovně inzulinemie a glykémie (cs)
  • We investigated glucose metabolism in septic patients during hyperglycemic clamps and compared the different levels of insulinemia and glycemia. Methods: In 10 nondiabetic. stable septic patients on mechanical ventilation with baseline glycemia > 6mmol/L and continuous insulin infusion, 3 steps of hyperinsulinemic clamp were performed after 8 hours without caloric intake. In step 1, the targets were insulinemia of 250 mIU/L and glycemia of 5mmol/; in step 2, insulinemia of 250 mIU/L and glycemia of 10 mmol/L; in step 3, insulinemia of 1250 mIU/L and glycemia of 5 mmol/L. Glucose uptake was calculated as the amount of glucose per time needed to maintain the target level of glycemia. Glucose oxidation was calculated from indirect calorimetry and urinary nitrogen losses. Values are provided as means +/- SD. A two-way analysis of variance and Scheffe's method were used for statistical analysis and p <.05 was considered significant. Results: At step 1, glucose uptake was lower than at step 2 (3.
  • We investigated glucose metabolism in septic patients during hyperglycemic clamps and compared the different levels of insulinemia and glycemia. Methods: In 10 nondiabetic. stable septic patients on mechanical ventilation with baseline glycemia > 6mmol/L and continuous insulin infusion, 3 steps of hyperinsulinemic clamp were performed after 8 hours without caloric intake. In step 1, the targets were insulinemia of 250 mIU/L and glycemia of 5mmol/; in step 2, insulinemia of 250 mIU/L and glycemia of 10 mmol/L; in step 3, insulinemia of 1250 mIU/L and glycemia of 5 mmol/L. Glucose uptake was calculated as the amount of glucose per time needed to maintain the target level of glycemia. Glucose oxidation was calculated from indirect calorimetry and urinary nitrogen losses. Values are provided as means +/- SD. A two-way analysis of variance and Scheffe's method were used for statistical analysis and p <.05 was considered significant. Results: At step 1, glucose uptake was lower than at step 2 (3. (en)
Title
  • Glycemia influences on glucose metabolism in sepsis during hyperinsulinemic clamp
  • Glycemia influences on glucose metabolism in sepsis during hyperinsulinemic clamp (en)
  • Vliv glykémie na metabolismus glukózy u sepsí při hyperinzulinovém clampu (cs)
skos:prefLabel
  • Glycemia influences on glucose metabolism in sepsis during hyperinsulinemic clamp
  • Glycemia influences on glucose metabolism in sepsis during hyperinsulinemic clamp (en)
  • Vliv glykémie na metabolismus glukózy u sepsí při hyperinzulinovém clampu (cs)
skos:notation
  • RIV/00216208:11120/05:00001033!RIV09-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 522835
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/05:00001033
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • critically ill patients; insulin-resistance; hyperglycemia; lactate; rat (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [C3F495848997]
http://linked.open...i/riv/nazevZdroje
  • Journal of Parenteral and Enteral Nutrition
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 29
http://linked.open...iv/tvurceVysledku
  • Těšínský, Pavel
  • Rušavý, Z.
  • Novák, I.
  • Šrámek, V.
  • Macdonald, I. A.
  • Lacigová, S.
http://linked.open...ain/vavai/riv/wos
  • 000228633300006
issn
  • 0148-6071
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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