About: Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions

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About: Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Avian schistosomes are the primary causative agent of cercarial dermatitis in humans, but despite its worldwide occurrence, little is known of the immune mechanism of this disease. Using a murine model, hosts were exposed to primary (I X) and multiple (4 x) infections of Trichobilharzia regenti via the pinna. Penetration of larvae into the skin evoked immediate edema, thickening of the exposure site, and an influx of leukocytes, including neutrophils, macrophages, CD4(+) lymphocytes, and mast cells. A large proportion of the latter were in the process of degranulating. After 1 x infection, inflammation was accompanied by the release of IL-1beta, IL-6, and IIL-12p40. In contrast, in 4 x reinfected animals the production of histamine, IL-4, and IL-10 was dramatically elevated within 1 h of infection. Avian schistosomes are the primary causative agent of cercarial dermatitis in humans, but despite its worldwide occurrence, little is known of the immune mechanism of this disease. Using a murine model, hosts were exposed to primary (I X) and multiple (4 x) infections of Trichobilharzia regenti via the pinna. Penetration of larvae into the skin evoked immediate edema, thickening of the exposure site, and an influx of leukocytes, including neutrophils, macrophages, CD4(+) lymphocytes, and mast cells. A large proportion of the latter were in the process of degranulating. After 1 x infection, inflammation was accompanied by the release of IL-1beta, IL-6, and IIL-12p40. In contrast, in 4 x reinfected animals the production of histamine, IL-4, and IL-10 was dramatically elevated within 1 h of infection. (en)
Title	Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions (en)
skos:prefLabel	Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions (en)
skos:notation	RIV/00216208:11120/04:00003624!RIV12-MZ0-11120___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA524/03/1263), P(NJ6718), Z(MSM 113100004)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kolářová, Libuše Kouřilová, Pavlína
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	557037
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/04:00003624
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Trichobilharzia-Regenti; Mast-Cells; Antibody-Responses; Immune-Responses; Dendritic Cells; Swimmers Itch; T-Cell; Histamine; Mansoni (en)
http://linked.open.../riv/klicoveSlovo	Histamine Mansoni Dendritic Cells Antibody-Responses Immune-Responses Mast-Cells Swimmers Itch T-Cell Trichobilharzia-Regenti
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[7BAAB5A2B4DD]
http://linked.open...i/riv/nazevZdroje	Journal of Immunology
http://linked.open...in/vavai/riv/obor	FN
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Interaction of bird schistosomes with target tissues and organs of vertebrates Pathogenesis of primoinfection and reinfection with bird schistosome cercariae
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	172
http://linked.open...iv/tvurceVysledku	Kolářová, Libuše Kouřilová, Pavlína
http://linked.open...ain/vavai/riv/wos	000220096000051
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20113100004
issn	0022-1767
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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