About: Morphological evidence of collateral sprouting of intact afferent and motor axons of the rat ulnar nerve demonstrated by one type of tracer molecule

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In our experimental paradigm we sutured the distal stump of a transected musculocutaneous nerve to an intact ulnar nerve of the rat in an end-to-side fashion. We demonstrated the formation of collateral sprouts from intact afferent and motor axons by application of one type of molecule conjugated by two different fluorophores (Fluoro-Ruby and Fluoro-Emerald). Fluoro-Ruby and Fluoro-Emerald were applied distal to end-to-side suture into fresh cut ends of the ulnar and musculocutaneous nerves, respectively. Formation of collateral sprouts was evidenced by findings of mixed (a yellow to orange color) fluorescence labeling of spinal motoneurons and dorsal root ganglia neurons. Colocalization of two different tracers retrogradely transported to the neurons was verified by the individual green and red fluorescence profiles analyzed by means of the computer-assisted image-analyzing system. In our experimental paradigm we sutured the distal stump of a transected musculocutaneous nerve to an intact ulnar nerve of the rat in an end-to-side fashion. We demonstrated the formation of collateral sprouts from intact afferent and motor axons by application of one type of molecule conjugated by two different fluorophores (Fluoro-Ruby and Fluoro-Emerald). Fluoro-Ruby and Fluoro-Emerald were applied distal to end-to-side suture into fresh cut ends of the ulnar and musculocutaneous nerves, respectively. Formation of collateral sprouts was evidenced by findings of mixed (a yellow to orange color) fluorescence labeling of spinal motoneurons and dorsal root ganglia neurons. Colocalization of two different tracers retrogradely transported to the neurons was verified by the individual green and red fluorescence profiles analyzed by means of the computer-assisted image-analyzing system. (en) Práce popisuje morfologický průkaz kolaterálního růstu intaktních aferentních a motorických axonů krysího ulnárního nervu demonstrovaný jedním typem molekuly izotopového indikátoru (cs)
Title	Morfologický průkaz kolaterálního růstu intaktních aferentních a motorických axonů krysího ulnárního nervu demonstrovaný jedním typem molekuly izotopového indikátoru (cs) Morphological evidence of collateral sprouting of intact afferent and motor axons of the rat ulnar nerve demonstrated by one type of tracer molecule Morphological evidence of collateral sprouting of intact afferent and motor axons of the rat ulnar nerve demonstrated by one type of tracer molecule (en)
skos:prefLabel	Morfologický průkaz kolaterálního růstu intaktních aferentních a motorických axonů krysího ulnárního nervu demonstrovaný jedním typem molekuly izotopového indikátoru (cs) Morphological evidence of collateral sprouting of intact afferent and motor axons of the rat ulnar nerve demonstrated by one type of tracer molecule Morphological evidence of collateral sprouting of intact afferent and motor axons of the rat ulnar nerve demonstrated by one type of tracer molecule (en)
skos:notation	RIV/00216208:11120/04:00001146!RIV/2005/MZ0/111205/N
http://linked.open.../vavai/riv/strany	231;234
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NF6658)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Šámal, Filip Haninec, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	574603
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/04:00001146
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Morphological;evidence;collateral;sprouting;intact;afferent;motor;axons;ulnar;nerve;demonstrated;tracer;molecule (en)
http://linked.open.../riv/klicoveSlovo	intact evidence motor molecule nerve demonstrated ulnar collateral sprouting Morphological tracer afferent axons
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[5D6AFE7196C9]
http://linked.open...i/riv/nazevZdroje	Annals of Anatomy
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Alternative approaches in brachial plexus reconstruction and experimental evaluation of various neurotrophic factors action on direct and collateral reinnervation
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	186
http://linked.open...iv/tvurceVysledku	Haninec, Pavel Šámal, Filip
issn	0940-9602
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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