About: Comparison of mutagenicity of selected natural chemical compounds in different tests for testing of mutagenicity

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Mutagenic, antimutagenic and immunomodulatory effects of plant compounds were studied in procaryotic (Salmonella typhimurium) and eucaryotic (male BALB C mice) models. Strong antimutagenic effect against AFB1 was found in cauliflower, carrot and garlic extracts. Extracts from cauliflower and carrot was also able significantly increase extremly low levels of chemiluminescence and blastic transformation, caused by AFB1 and heterocyclic amines from protein pyrolyzate. Some plant compounds (-angelikalactone, juglone, humulone, emodine, hypericine, psoralene) revealed mutagenic activity. Strong antimutagenic effect of plant phenol ellagic acid against mutagenicity of AFB1 and amino-methylimidazo-quinoline (IQ) were detected in Ames and micronucleus tests. Mutagenic, antimutagenic and immunomodulatory effects of plant compounds were studied in procaryotic (Salmonella typhimurium) and eucaryotic (male BALB C mice) models. Strong antimutagenic effect against AFB1 was found in cauliflower, carrot and garlic extracts. Extracts from cauliflower and carrot was also able significantly increase extremly low levels of chemiluminescence and blastic transformation, caused by AFB1 and heterocyclic amines from protein pyrolyzate. Some plant compounds (-angelikalactone, juglone, humulone, emodine, hypericine, psoralene) revealed mutagenic activity. Strong antimutagenic effect of plant phenol ellagic acid against mutagenicity of AFB1 and amino-methylimidazo-quinoline (IQ) were detected in Ames and micronucleus tests. (en)
Title	Comparison of mutagenicity of selected natural chemical compounds in different tests for testing of mutagenicity Comparison of mutagenicity of selected natural chemical compounds in different tests for testing of mutagenicity (en)
skos:prefLabel	Comparison of mutagenicity of selected natural chemical compounds in different tests for testing of mutagenicity Comparison of mutagenicity of selected natural chemical compounds in different tests for testing of mutagenicity (en)
skos:notation	RIV/00216208:11120/01:00110191!RIV/2002/GA0/111202/N
http://linked.open.../vavai/riv/strany	15;11
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA311/94/1739), P(IZ4147), P(NJ6138), Z(MSM 111200001)
http://linked.open...vai/riv/dodaniDat	2002
http://linked.open...aciTvurceVysledku	Šmerák, Petr Polívková, Zdeňka Bártová, Jiřina Bárta, Ivo Langová, Martina
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	676006
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/01:00110191
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Comparison;mutagenicity;selected;natural;chemical;compounds;different;tests;testing;mutagenicity (en)
http://linked.open.../riv/klicoveSlovo	Comparison different testing chemical mutagenicity compounds natural tests selected
http://linked.open...ontrolniKodProRIV	[19335E408993]
http://linked.open...v/mistoKonaniAkce	Riva del Garda
http://linked.open...i/riv/mistoVydani	Riva del Garda
http://linked.open...i/riv/nazevZdroje	Abstracts of Federazione Italiana Scienze della Vita
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of antimutagenic effect and immunomodulatory activity of natural substances Study of Health Safety of Foodstuffs of Plant Origin with Regard to Natural Toxicants and Mycotoxins Biological effects of selected mycotoxins and their combinations
http://linked.open...UplatneniVysledku	2001
http://linked.open...iv/tvurceVysledku	Bártová, Jiřina Bárta, Ivo Polívková, Zdeňka Šmerák, Petr Langová, Martina
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2001-01-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111200001
number of pages	3 (xsd:int)
http://purl.org/ne...btex#hasPublisher	FISV
http://localhost/t...ganizacniJednotka	11120

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