About: Postmitotic basal cells in squamous cell epithelia are identified with Dolichos biflorus agglutinin

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About: Postmitotic basal cells in squamous cell epithelia are identified with Dolichos biflorus agglutinin - functional consequences Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1034/j.1600-0463.2001.d01-137.x
Description	Dolichos biflorus agglutinin (DBA) is a plant lectin specifically recognizing alpha -N-acetylgalactosamine. Controversial reports regarding the binding of DBA to the epidermis have been published. Using a double labeling procedure at the single-cell level, we studied the expression of DBA-reactive binding sites in conjunction with markers, of cell proliferation and differentiation in normal human epidermis, cornea, and malignant tumors as well as in cultured keratinocytes. The results characterize the cells recognized by DBA as postmitotic early differentiating cells, identifiable by their lack of expression of the proliferation marker (Ki-67). The Golgi complex of a limited number of cultured keratinocytes was, recognized by DBA and some of these cells show the accumulation of beta (1) integrin chain in the Golgi complex. This process seems to be important for the migration of postmitotic cells from the basal to the suprabasal layers. Dolichos biflorus agglutinin (DBA) is a plant lectin specifically recognizing alpha -N-acetylgalactosamine. Controversial reports regarding the binding of DBA to the epidermis have been published. Using a double labeling procedure at the single-cell level, we studied the expression of DBA-reactive binding sites in conjunction with markers, of cell proliferation and differentiation in normal human epidermis, cornea, and malignant tumors as well as in cultured keratinocytes. The results characterize the cells recognized by DBA as postmitotic early differentiating cells, identifiable by their lack of expression of the proliferation marker (Ki-67). The Golgi complex of a limited number of cultured keratinocytes was, recognized by DBA and some of these cells show the accumulation of beta (1) integrin chain in the Golgi complex. This process seems to be important for the migration of postmitotic cells from the basal to the suprabasal layers. (en)
Title	Postmitotic basal cells in squamous cell epithelia are identified with Dolichos biflorus agglutinin - functional consequences Postmitotic basal cells in squamous cell epithelia are identified with Dolichos biflorus agglutinin - functional consequences (en)
skos:prefLabel	Postmitotic basal cells in squamous cell epithelia are identified with Dolichos biflorus agglutinin - functional consequences Postmitotic basal cells in squamous cell epithelia are identified with Dolichos biflorus agglutinin - functional consequences (en)
skos:notation	RIV/00216208:11120/01:00003762!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/00/1310), P(KSK4055109), Z(AV0Z4050913), Z(MSM 111100005), Z(MSM 111200001)
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Dvořánková, Barbora
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	691976
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/01:00003762
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	squamous cell epithelia; carcinoma; lectin; Dolichos biflorus agglutinin; integrin; differentiation (en)
http://linked.open.../riv/klicoveSlovo	carcinoma lectin integrin Dolichos biflorus agglutinin squamous cell epithelia differentiation
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[989D47385068]
http://linked.open...i/riv/nazevZdroje	APMIS
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Physics, chemistry and informatics for biological, ecological and medicinal applications Development of supports for keratinocyte grafting with covalently bound carbohydrates for study of keratinocyte differentiation and subsequentmedicalapplication
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	109
http://linked.open...iv/tvurceVysledku	Dvořánková, Barbora Hrdličková-Celá, E.
http://linked.open...ain/vavai/riv/wos	000172005500011
http://linked.open...n/vavai/riv/zamer	Cílená syntéza a studium chemických, fyzikálně-chemických a fyzikálních vlastností makromolekulárních a nadmolekulárních látek a soustav pro vyspělé technologie http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111100005 http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111200001
issn	0903-4641
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1034/j.1600-0463.2001.d01-137.x
http://localhost/t...ganizacniJednotka	11120

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