About: Comparison of two different methods for CD34+ selection and T cell depletion in peripheral blood stem cell grafts - Our experiences with CellPro, E rosetting and CliniMACS technique

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About: Comparison of two different methods for CD34+ selection and T cell depletion in peripheral blood stem cell grafts - Our experiences with CellPro, E rosetting and CliniMACS technique Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of this study was to establish a suitable method for in vitro T cell depletion in peripheral blood ste in cell grafts for mismatched/haploidentical transplantation in children and adults with severe hematological disorders and for autologous transplantation in patients with autoimmune diseases refractory to conventional immunosuppressive treatment. Two different selection techniques have been used: CD34+ selection using immunoaffinity columns (CellPro Ceprate) followed by T cell depletion by E-rosetting or CD34+ selection using submicroscopic paramagnetic beads (CliniMACS device) with T cell depletion in a one step procedure. The mean purity and recovery of CD34+ cells and efficiency of T cell removal in the final product were compared The aim of this study was to establish a suitable method for in vitro T cell depletion in peripheral blood ste in cell grafts for mismatched/haploidentical transplantation in children and adults with severe hematological disorders and for autologous transplantation in patients with autoimmune diseases refractory to conventional immunosuppressive treatment. Two different selection techniques have been used: CD34+ selection using immunoaffinity columns (CellPro Ceprate) followed by T cell depletion by E-rosetting or CD34+ selection using submicroscopic paramagnetic beads (CliniMACS device) with T cell depletion in a one step procedure. The mean purity and recovery of CD34+ cells and efficiency of T cell removal in the final product were compared (en)
Title	Comparison of two different methods for CD34+ selection and T cell depletion in peripheral blood stem cell grafts - Our experiences with CellPro, E rosetting and CliniMACS technique Comparison of two different methods for CD34+ selection and T cell depletion in peripheral blood stem cell grafts - Our experiences with CellPro, E rosetting and CliniMACS technique (en)
skos:prefLabel	Comparison of two different methods for CD34+ selection and T cell depletion in peripheral blood stem cell grafts - Our experiences with CellPro, E rosetting and CliniMACS technique Comparison of two different methods for CD34+ selection and T cell depletion in peripheral blood stem cell grafts - Our experiences with CellPro, E rosetting and CliniMACS technique (en)
skos:notation	RIV/00216208:11120/01:00003672!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IZ3561), P(NE4554), Z(MSM 111200002)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kozák, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	676040
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/01:00003672
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	CD34+selection; T cell depletion; PBSC; immunorosettes; CellPro; CliniMACS (en)
http://linked.open.../riv/klicoveSlovo	PBSC CD34+selection CellPro CliniMACS T cell depletion immunorosettes
http://linked.open...odStatuVydavatele	SK - Slovenská republika
http://linked.open...ontrolniKodProRIV	[43D73CF071CA]
http://linked.open...i/riv/nazevZdroje	Neoplasma
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Processing and purging of haematopoietic cells grafts ex vivo before their transplantation. Unrelated bone marrow transplantation with T - cell depletion in children with leukemia and nonhematological disorders
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	48
http://linked.open...iv/tvurceVysledku	Kozák, Tomáš Poloučková, A.
http://linked.open...ain/vavai/riv/wos	000172665400007
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111200002
issn	0028-2685
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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