About: Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner     Goto   Sponge   NotDistinct   Permalink

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Description
  • Bicuculline was used to investigate seizure susceptibility in pre- and peripubertal male and female rats exposed prenatally to morphine. Morphine-exposed males showed increased seizure susceptibility at prepubertal and decreased susceptibility at peripubertal ages. There was no difference in seizure susceptibility in morphine-exposed females at either age. Therefore, the present data suggest that males are more vulnerable than females to morphine-induced insults during prenatal brain development.
  • Bicuculline was used to investigate seizure susceptibility in pre- and peripubertal male and female rats exposed prenatally to morphine. Morphine-exposed males showed increased seizure susceptibility at prepubertal and decreased susceptibility at peripubertal ages. There was no difference in seizure susceptibility in morphine-exposed females at either age. Therefore, the present data suggest that males are more vulnerable than females to morphine-induced insults during prenatal brain development. (en)
Title
  • Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner
  • Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner (en)
skos:prefLabel
  • Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner
  • Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner (en)
skos:notation
  • RIV/00216208:11120/00:00003745!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM 111200005)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...dnocenehoVysledku
  • 722905
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/00:00003745
http://linked.open...riv/jazykVysledku
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  • Epilepsy; Prenatal drug exposure; Opiates; Development; Gender (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [06CB752B6833]
http://linked.open...i/riv/nazevZdroje
  • Developmental Brain Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 121
http://linked.open...iv/tvurceVysledku
  • Šlamberová, Romana
  • Vathy, Ilona
  • Velíšková, Jana
  • Schindler, C. J.
http://linked.open...ain/vavai/riv/wos
  • 000087406900014
http://linked.open...n/vavai/riv/zamer
issn
  • 0165-3806
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/S0165-3806(00)00031-6
http://localhost/t...ganizacniJednotka
  • 11120
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