About: Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis     Goto   Sponge   NotDistinct   Permalink

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Description
  • DNA samples of 523 unrelated anonymized individuals (307 males and 216 females) born and living in the Czech Republic were genotyped using Investigator (R) Argus X-12 system in the following loci localized in four linkage groups: DXS10148, DXS10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146, DXS10134, DXS742. Haplotype frequencies were calculated for each LG (Linkage Group). The frequency of most common haplotype was 0.016, 0.036, 0.042, and 0.023 for LG1, LG2, LG3, and LG4, respectively. The combined power of discrimination was more than 0.999999999 both for female and male samples. The mean exclusion chance was 0.99999999 (trios) and 0.999999 (duos). Informativity and suitability of Investigator (R) Argus X-12 for kinship determination was assessed by computing in several female-female duos using LR (Likelihood Ratio) determination for autosomal STR (PowerPlex ESI-17), linked (Investigator (R) Argus X-12 system), and unlinked (X-STR Decaplex) X-STR kits. Investigator (R) Argus X-12 proved to be very useful for sibship determination, since its LR values were relatively similar to LR for autosomal STR kit. This work presents the first population data for Investigator (R) Argus X-12 system in the Czech Republic.
  • DNA samples of 523 unrelated anonymized individuals (307 males and 216 females) born and living in the Czech Republic were genotyped using Investigator (R) Argus X-12 system in the following loci localized in four linkage groups: DXS10148, DXS10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146, DXS10134, DXS742. Haplotype frequencies were calculated for each LG (Linkage Group). The frequency of most common haplotype was 0.016, 0.036, 0.042, and 0.023 for LG1, LG2, LG3, and LG4, respectively. The combined power of discrimination was more than 0.999999999 both for female and male samples. The mean exclusion chance was 0.99999999 (trios) and 0.999999 (duos). Informativity and suitability of Investigator (R) Argus X-12 for kinship determination was assessed by computing in several female-female duos using LR (Likelihood Ratio) determination for autosomal STR (PowerPlex ESI-17), linked (Investigator (R) Argus X-12 system), and unlinked (X-STR Decaplex) X-STR kits. Investigator (R) Argus X-12 proved to be very useful for sibship determination, since its LR values were relatively similar to LR for autosomal STR kit. This work presents the first population data for Investigator (R) Argus X-12 system in the Czech Republic. (en)
Title
  • Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis
  • Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis (en)
skos:prefLabel
  • Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis
  • Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis (en)
skos:notation
  • RIV/00216208:11110/14:10292401!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 14
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 22787
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/14:10292401
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • X-STR Decaplex; X-STR; Kinship analysis; Investigator (R) Argus X-12; Forensic genetics (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [98B52318C1C0]
http://linked.open...i/riv/nazevZdroje
  • Electrophoresis
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 35
http://linked.open...iv/tvurceVysledku
  • Hořínek, Aleš
  • Zidkova, Anastassiya
  • Capek, Pavel
  • Coufalova, Pavla
http://linked.open...ain/vavai/riv/wos
  • 000339661300008
issn
  • 0173-0835
number of pages
http://bibframe.org/vocab/doi
  • 10.1002/elps.201400046
http://localhost/t...ganizacniJednotka
  • 11110
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