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  • Over the last two decades, the amount of evidence corroborating an association between dental plaque bacteria and coronary diseases that develop as a result of atherosclerosis has increased. These findings have brought a new aspect to the etiology of the disease. There are several mechanisms by which dental plaque bacteria may initiate or worsen atherosclerotic processes: activation of innate immunity, bacteremia related to dental treatment, and direct involvement of mediators activated by dental plaque and involvement of cytokines and heat shock proteins from dental plaque bacteria. There are common predisposing factors which influence both periodontitis and atherosclerosis. Both diseases can be initiated in early childhood, although the first symptoms may not appear until adulthood. The formation of lipid stripes has been reported in 10-year-old children and the increased prevalence of obesity in children and adolescents is a risk factor contributing to lipid stripes development. Endotheliumdamage caused by the formation of lipid stripes in early childhood may lead to bacteria penetrating into blood circulation after oral cavity procedures for children as well as for patients with aggressive and chronic periodontitis.
  • Over the last two decades, the amount of evidence corroborating an association between dental plaque bacteria and coronary diseases that develop as a result of atherosclerosis has increased. These findings have brought a new aspect to the etiology of the disease. There are several mechanisms by which dental plaque bacteria may initiate or worsen atherosclerotic processes: activation of innate immunity, bacteremia related to dental treatment, and direct involvement of mediators activated by dental plaque and involvement of cytokines and heat shock proteins from dental plaque bacteria. There are common predisposing factors which influence both periodontitis and atherosclerosis. Both diseases can be initiated in early childhood, although the first symptoms may not appear until adulthood. The formation of lipid stripes has been reported in 10-year-old children and the increased prevalence of obesity in children and adolescents is a risk factor contributing to lipid stripes development. Endotheliumdamage caused by the formation of lipid stripes in early childhood may lead to bacteria penetrating into blood circulation after oral cavity procedures for children as well as for patients with aggressive and chronic periodontitis. (en)
Title
  • Periodontitis as a Risk Factor of Atherosclerosis
  • Periodontitis as a Risk Factor of Atherosclerosis (en)
skos:prefLabel
  • Periodontitis as a Risk Factor of Atherosclerosis
  • Periodontitis as a Risk Factor of Atherosclerosis (en)
skos:notation
  • RIV/00216208:11110/14:10285523!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • March
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 36196
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/14:10285523
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • epithelial-cells; autoimmune-disease; scientific statement; shock-protein; cardiovascular-disease; porphyromonas-gingivalis; necrosis-factor-alpha; peripheral arterial-disease; c-reactive protein; coronary-heart-disease (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [1E8B8DDEE095]
http://linked.open...i/riv/nazevZdroje
  • Journal of Immunology Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 2014
http://linked.open...iv/tvurceVysledku
  • Podzimek, Štěpán
  • Procházková, Jarmila
  • Dušková, Jana
  • Bártová, Jiřina
  • Sommerová, Pavla
  • Lyuya-Mi, Yelena
  • Janatová, Taťjana
  • Myšák, Jaroslav
http://linked.open...ain/vavai/riv/wos
  • 000333835400001
issn
  • 2314-8861
number of pages
http://bibframe.org/vocab/doi
  • 10.1155/2014/636893
http://localhost/t...ganizacniJednotka
  • 11110
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