About: The Nuclear Receptor Constitutive Androstane Receptor/NR1I3 Enhances the Profibrotic Effects of Transforming Growth Factor beta and Contributes to the Development of Experimental Dermal Fibrosis     Goto   Sponge   NotDistinct   Permalink

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Description
  • CAR is upregulated in SSc and regulates TGF-β signaling. Activation of CAR increases the profibrotic effects of TGF-β in cultured fibroblasts and in different preclinical models of SSc. Thus, inactivation of CAR might be a novel approach to target aberrant TGF-β signaling in SSc and in other fibrotic diseases
  • CAR is upregulated in SSc and regulates TGF-β signaling. Activation of CAR increases the profibrotic effects of TGF-β in cultured fibroblasts and in different preclinical models of SSc. Thus, inactivation of CAR might be a novel approach to target aberrant TGF-β signaling in SSc and in other fibrotic diseases (en)
Title
  • The Nuclear Receptor Constitutive Androstane Receptor/NR1I3 Enhances the Profibrotic Effects of Transforming Growth Factor beta and Contributes to the Development of Experimental Dermal Fibrosis
  • The Nuclear Receptor Constitutive Androstane Receptor/NR1I3 Enhances the Profibrotic Effects of Transforming Growth Factor beta and Contributes to the Development of Experimental Dermal Fibrosis (en)
skos:prefLabel
  • The Nuclear Receptor Constitutive Androstane Receptor/NR1I3 Enhances the Profibrotic Effects of Transforming Growth Factor beta and Contributes to the Development of Experimental Dermal Fibrosis
  • The Nuclear Receptor Constitutive Androstane Receptor/NR1I3 Enhances the Profibrotic Effects of Transforming Growth Factor beta and Contributes to the Development of Experimental Dermal Fibrosis (en)
skos:notation
  • RIV/00216208:11110/14:10285291!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 11
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 33228
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/14:10285291
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • TGF-β; nuclear receptor; fibroblasts; scleroderma; systemic sclerosis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [C3C15BA58933]
http://linked.open...i/riv/nazevZdroje
  • Arthritis & Rheumatology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 66
http://linked.open...iv/tvurceVysledku
  • Avouac, Jerome
  • Beyer, Christian
  • Dees, Clara
  • Distler, Oliver
  • Tomčík, Michal
  • Zerr, Pawel
  • Distler, Alfiya
  • Palumbo-Zerr, Katrin
  • Distler, Joerg H. W.
  • Schett, Georg
  • Allanore, Yannick
  • Ruzehaji, Nadira
  • Schneider, Holm
http://linked.open...ain/vavai/riv/wos
  • 000344349500024
issn
  • 2326-5191
number of pages
http://bibframe.org/vocab/doi
  • 10.1002/art.38819
http://localhost/t...ganizacniJednotka
  • 11110
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