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Description
  • The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe possibly due to changes in environmental factors towards a more %22westernised%22 standard of living. The aim of this study was to investigate differences in exposure to environmental factors prior to diagnosis in Eastern and Western European IBD patients. Methods: The EpiCom cohort is a population-based, prospective inception cohort of 1560 unselected IBD patients from 31 European countries covering a background population of 10.1 million. At the time of diagnosis patients were asked to complete an 87-item questionnaire concerning environmental factors. Results: A total of 1182 patients (76%) answered the questionnaire, 444 (38%) had Crohn's disease (CD), 627 (53%) ulcerative colitis (UC), and 111 (9%) IBD unclassified. No geographic differences regarding smoking status, caffeine intake, use of oral contraceptives, or number of first-degree relatives with IBD were found. Sugar intake was higher in CD and UC patients from Eastern Europe than in Western Europe while fibre intake was lower (p b 0.01). Daily consumption of fast food as well as appendectomy before the age of 20 was more frequent in Eastern European than in Western European UC patients (p b 0.01). Eastern European CD and UC patients had received more vaccinations and experienced fewer childhood infections than Western European patients (p b 0.01). Conclusions: In this European population-based inception cohort of unselected IBD patients, Eastern and Western European patients differed in environmental factors prior to diagnosis. Eastern European patients exhibited
  • The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe possibly due to changes in environmental factors towards a more %22westernised%22 standard of living. The aim of this study was to investigate differences in exposure to environmental factors prior to diagnosis in Eastern and Western European IBD patients. Methods: The EpiCom cohort is a population-based, prospective inception cohort of 1560 unselected IBD patients from 31 European countries covering a background population of 10.1 million. At the time of diagnosis patients were asked to complete an 87-item questionnaire concerning environmental factors. Results: A total of 1182 patients (76%) answered the questionnaire, 444 (38%) had Crohn's disease (CD), 627 (53%) ulcerative colitis (UC), and 111 (9%) IBD unclassified. No geographic differences regarding smoking status, caffeine intake, use of oral contraceptives, or number of first-degree relatives with IBD were found. Sugar intake was higher in CD and UC patients from Eastern Europe than in Western Europe while fibre intake was lower (p b 0.01). Daily consumption of fast food as well as appendectomy before the age of 20 was more frequent in Eastern European than in Western European UC patients (p b 0.01). Eastern European CD and UC patients had received more vaccinations and experienced fewer childhood infections than Western European patients (p b 0.01). Conclusions: In this European population-based inception cohort of unselected IBD patients, Eastern and Western European patients differed in environmental factors prior to diagnosis. Eastern European patients exhibited (en)
Title
  • Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study
  • Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study (en)
skos:prefLabel
  • Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study
  • Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study (en)
skos:notation
  • RIV/00216208:11110/14:10283821!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 7
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 14762
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/14:10283821
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Europe; patients; bowel disease; inflammatory; cohort; population-based inception; factors; Environmental (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [010B8E567C8D]
http://linked.open...i/riv/nazevZdroje
  • Journal of Crohn's and Colitis
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 8
http://linked.open...iv/tvurceVysledku
  • Pedersen, N.
  • Ďuricová, Dana
  • Bortlík, Martin
  • Tsianos, E. V.
  • Collin, P.
  • Lakatos, L.
  • Andersen, V.
  • Avnstrom, S.
  • Bailey, Y.
  • Bjornsson, E.
  • Burisch, J.
  • Cukovic-Cavka, S.
  • Dahlerup, J. F.
  • Kaimakliotis, I.
  • Katsanos, K. H.
  • Kjeldsen, J.
  • Krabbe, S.
  • Ladefoged, K.
  • Manninen, P.
  • Nielsen, K. R.
  • O'Morain, C.
  • Odes, S.
  • Olsen, J.
  • Ragnarsson, G.
  • Salupere, R.
  • Schwartz, D.
  • Shonova, O.
  • Thorsgaard, N.
  • Turk, N.
  • Vind, I.
http://linked.open...ain/vavai/riv/wos
  • 000337867700006
issn
  • 1873-9946
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.crohns.2013.11.021
http://localhost/t...ganizacniJednotka
  • 11110
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