About: Does folic acid supplementation rescue defects in ECE-1-deficient mouse embryos?

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://fb.cuni.cz/file/5758/fb2014a0045.pdf
Description	FA supplementation did not result in modified proportions of the genotypes, indicating no rescue of the embryonic mortality. There was also no effect on the litter size. Craniofacial and cardiac defects were likewise identical in the ECE1 embryos of both groups. These results caution against indiscriminate use of dietary supplements in attempts to prevent congenital anomalies. FA supplementation did not result in modified proportions of the genotypes, indicating no rescue of the embryonic mortality. There was also no effect on the litter size. Craniofacial and cardiac defects were likewise identical in the ECE1 embryos of both groups. These results caution against indiscriminate use of dietary supplements in attempts to prevent congenital anomalies. (en)
Title	Does folic acid supplementation rescue defects in ECE-1-deficient mouse embryos? Does folic acid supplementation rescue defects in ECE-1-deficient mouse embryos? (en)
skos:prefLabel	Does folic acid supplementation rescue defects in ECE-1-deficient mouse embryos? Does folic acid supplementation rescue defects in ECE-1-deficient mouse embryos? (en)
skos:notation	RIV/00216208:11110/14:10279718!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(GA13-12412S), P(GAP302/11/1308), S
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Kvasilová, Alena Sedmera, David Krejčí, Eliška Šaňková, Barbora Haque, Ayesha
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	12092
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/14:10279718
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	endothelin receptor; cardiac malformations; endothelin 1; mice; endothelin-converting enzyme (en)
http://linked.open.../riv/klicoveSlovo	cardiac malformations endothelin 1 endothelin receptor endothelin-converting enzyme mice
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[63A7A02E3B1D]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Epigenetic factors in myocardial morphogenesis Development of mouse conduction system analyzed by 3D imaging and optical mapping
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	60
http://linked.open...iv/tvurceVysledku	Sedmera, David Krejčí, Eliška Šaňková, Barbora Haque, Ayesha Kvasilová, Alena
http://linked.open...ain/vavai/riv/wos	000346234100006
issn	0015-5500
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	11110

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