About: Pentosidine, an Advaced Glycation End_Product, May Reflect Clinical and Morphological Features and Hand Osteoarthritis

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Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377906/
Description	The study investigates pentosidine levels, an advanced glycation end-product, in patients with erosive and non-erosive hand osteoarthritis (HOA) and determine its potential association with clinical findings and imaging-defined joint damage. The levels of urine pentosidine, but not of serum pentosidine, were higher in patients with erosive HOA than in non-erosive HOA and correlated with CRP, and AUSCAN. Serum pentosidine, but not in urine, significantly correlated with the Kallman radiographic score in erosive HOA at the baseline and after 2years. Our data suggest that serum and urine pentosidine levels may relate to the distinctive clinical and morphological features of HOA. The study investigates pentosidine levels, an advanced glycation end-product, in patients with erosive and non-erosive hand osteoarthritis (HOA) and determine its potential association with clinical findings and imaging-defined joint damage. The levels of urine pentosidine, but not of serum pentosidine, were higher in patients with erosive HOA than in non-erosive HOA and correlated with CRP, and AUSCAN. Serum pentosidine, but not in urine, significantly correlated with the Kallman radiographic score in erosive HOA at the baseline and after 2years. Our data suggest that serum and urine pentosidine levels may relate to the distinctive clinical and morphological features of HOA. (en)
Title	Pentosidine, an Advaced Glycation End_Product, May Reflect Clinical and Morphological Features and Hand Osteoarthritis Pentosidine, an Advaced Glycation End_Product, May Reflect Clinical and Morphological Features and Hand Osteoarthritis (en)
skos:prefLabel	Pentosidine, an Advaced Glycation End_Product, May Reflect Clinical and Morphological Features and Hand Osteoarthritis Pentosidine, an Advaced Glycation End_Product, May Reflect Clinical and Morphological Features and Hand Osteoarthritis (en)
skos:notation	RIV/00216208:11110/12:12829!RIV13-MSM-11110___
http://linked.open...avai/predkladatel	1. lékařská fakulta
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Pavelka, Karel Kaspříková, Nikola Šenolt, Ladislav Vencovský, Jiří Šléglová, Olga Gatterová, Jindřiška
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	158127
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/12:12829
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	hand osteoarthritis(HOA); pentosidine; erosive disease; biomarker; radiographs (en)
http://linked.open.../riv/klicoveSlovo	erosive disease hand osteoarthritis(HOA) pentosidine radiographs biomarker
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[44E853850334]
http://linked.open...i/riv/nazevZdroje	The Open Rheumatology Journal
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	2012
http://linked.open...iv/tvurceVysledku	Filková, Mária Kaspříková, Nikola Pavelka, Karel Vencovský, Jiří Šenolt, Ladislav Hulejová, Hana Gatterová, Jindřiška Šléglová, Olga Braun, Martin Pavelková, Andrea
issn	1874-3129
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	11110
is http://linked.open...avai/riv/vysledek of	Pentosidine, an Advaced Glycation End_Product, May Reflect Clinical and Morphological Features and Hand Osteoarthritis

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