About: Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals     Goto   Sponge   NotDistinct   Permalink

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Description
  • We investigated the changes in gene expression, receptor number, echocardiography, muscarinic/adrenergic agonist/antagonist changes in heart rate (HR) and HR biorhythm in M-2 KO mice (mice lacking the main cardioinhibitory receptors) in the left ventricle (LV) and right ventricle (RV). We can conclude that although the main cardioinhobitory receptors are not present in the heart, the function is not much affected.
  • We investigated the changes in gene expression, receptor number, echocardiography, muscarinic/adrenergic agonist/antagonist changes in heart rate (HR) and HR biorhythm in M-2 KO mice (mice lacking the main cardioinhibitory receptors) in the left ventricle (LV) and right ventricle (RV). We can conclude that although the main cardioinhobitory receptors are not present in the heart, the function is not much affected. (en)
Title
  • Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals
  • Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals (en)
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  • Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals
  • Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals (en)
skos:notation
  • RIV/00216208:11110/12:11500!RIV13-GA0-11110___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA309/09/0406)
http://linked.open...iv/cisloPeriodika
  • 12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 129798
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  • RIV/00216208:11110/12:11500
http://linked.open...riv/jazykVysledku
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  • M-2 muscarinic receptor knockout; Beta-adrenoceptors; biorhytms; echocardiography; telemetry; heart rate; activity; temperature (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [87B19C42200C]
http://linked.open...i/riv/nazevZdroje
  • Naunyn-Schmiedebergs Archives of Pharmacology
http://linked.open...in/vavai/riv/obor
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 385
http://linked.open...iv/tvurceVysledku
  • Nováková, Martina
  • Beneš, Jan
  • Mysliveček, Jaromír
  • Farár, Vladimír
  • Vařejková, Eva
http://linked.open...ain/vavai/riv/wos
  • 000310962000002
issn
  • 0028-1298
number of pages
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  • 11110
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