Expression of p53 and its isoforms was studied in melanoma cell lines. p53 beta and delta40p53 mRNA were revealed in melanoma cell instead of fibroblasts and melanocytes and their expression was influenced by cisplatin treatment.
Expression of p53 and its isoforms was studied in melanoma cell lines. p53 beta and delta40p53 mRNA were revealed in melanoma cell instead of fibroblasts and melanocytes and their expression was influenced by cisplatin treatment. (en)
Byla studovány exprese p53 a jeho izoforem v buněčných liniích melanomu. p53beta a delta40p53 byly detkovány na hladině mRNA v buňkách melanomu, nikoliv však ve fibroblastech a melanocytech. Exprese izoforem byla ovlivněna cisplatinou. (cs)