About: Cellular cohesiveness in benign and malignant thyroid follicular tumours varies significantly, but the difference is not useful in diagnosis of individual cases     Goto   Sponge   NotDistinct   Permalink

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  • The aim of our study was to search for new, readily available and statistically reliable cytological markers for differentiating benign and malignant follicular thyroid neoplasms pre-operatively. Although we demonstrated on the cohort of 58 cases (48 follicular adenomas, 10 follicular carcinomas) a statistically significant difference in cell cohesion, these could not be distinguished in the clinical setting because the specificity was too low. The absence of correlation of cellular cohesiveness with E-cadherin expression indicates that other factors are probably responsible for the loss of cohesiveness observed in follicular thyroid malignancy.
  • The aim of our study was to search for new, readily available and statistically reliable cytological markers for differentiating benign and malignant follicular thyroid neoplasms pre-operatively. Although we demonstrated on the cohort of 58 cases (48 follicular adenomas, 10 follicular carcinomas) a statistically significant difference in cell cohesion, these could not be distinguished in the clinical setting because the specificity was too low. The absence of correlation of cellular cohesiveness with E-cadherin expression indicates that other factors are probably responsible for the loss of cohesiveness observed in follicular thyroid malignancy. (en)
Title
  • Cellular cohesiveness in benign and malignant thyroid follicular tumours varies significantly, but the difference is not useful in diagnosis of individual cases
  • Cellular cohesiveness in benign and malignant thyroid follicular tumours varies significantly, but the difference is not useful in diagnosis of individual cases (en)
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  • Cellular cohesiveness in benign and malignant thyroid follicular tumours varies significantly, but the difference is not useful in diagnosis of individual cases
  • Cellular cohesiveness in benign and malignant thyroid follicular tumours varies significantly, but the difference is not useful in diagnosis of individual cases (en)
skos:notation
  • RIV/00179906:_____/12:10125275!RIV13-MZ0-00179906
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  • I
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  • 1
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  • 126231
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  • RIV/00179906:_____/12:10125275
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  • carcinoma.; adenoma; cellular cohesiveness; E-cadherin; thyroid gland; follicular lesion; Fine needle aspiration cytology (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [AC478FD8221D]
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  • Cytopathology
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  • 23
http://linked.open...iv/tvurceVysledku
  • Laco, Jan
  • Ryška, Aleš
  • Čáp, Jan
  • Rozkoš, Tomáš
  • Sobande, Folakemi Ayotunde
http://linked.open...ain/vavai/riv/wos
  • 000299099600006
issn
  • 0956-5507
number of pages
http://bibframe.org/vocab/doi
  • 10.1111/j.1365-2303.2010.00834.x
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