About: Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy

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About: Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.nature.com/hr/journal/v34/n1/full/hr2010183a.html
Description	Difficult-to-control arterial hypertension is a common medical problem that may result from severe hypertensive disease or from poor adherence to the recommended medical treatment. The use of serum levels of prescribed antihypertensive drugs to evaluate the adherence in individuals with difficult-to-control arterial hypertension was descibed. Serum drug levels (SDLs) were evaluated by liquid chromatography with mass spectrometry. Eighty-four patients who presented with uncontrolled blood pressure despite the recommended combination of at least three antihypertensives were enrolled in the study. In 55 (65.5%) patients, non-adherence was diagnosed. Our data suggest that an assessment of SDLs might be helpful before an extensive evaluation is initiated for difficult-to-control hypertension. Difficult-to-control arterial hypertension is a common medical problem that may result from severe hypertensive disease or from poor adherence to the recommended medical treatment. The use of serum levels of prescribed antihypertensive drugs to evaluate the adherence in individuals with difficult-to-control arterial hypertension was descibed. Serum drug levels (SDLs) were evaluated by liquid chromatography with mass spectrometry. Eighty-four patients who presented with uncontrolled blood pressure despite the recommended combination of at least three antihypertensives were enrolled in the study. In 55 (65.5%) patients, non-adherence was diagnosed. Our data suggest that an assessment of SDLs might be helpful before an extensive evaluation is initiated for difficult-to-control hypertension. (en)
Title	Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy (en)
skos:prefLabel	Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy (en)
skos:notation	RIV/00179906:_____/11:10081782!RIV12-MZ0-00179906
http://linked.open...avai/predkladatel	Fakultní nemocnice Hradec Králové
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021620817), Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Voříšek, Viktor Habrdová, Vilma Pelouch, Radek Solař, Miroslav Ceral, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	194601
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/11:10081782
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mass spectrometry; chromatography liquid; medication adherence; antihypertensive agents; drug therapy; hypertension (en)
http://linked.open.../riv/klicoveSlovo	hypertension - ischaemic heart disease - cardiac failure - vitamin D mass spectrometry antihypertensive agents chromatography liquid drug therapy medication adherence
http://linked.open...odStatuVydavatele	JP - Japonsko
http://linked.open...ontrolniKodProRIV	[5AAC8972DE76]
http://linked.open...i/riv/nazevZdroje	Hypertension Research
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	34
http://linked.open...iv/tvurceVysledku	Ceral, Jiří Solař, Miroslav Voříšek, Viktor Bíma, Marcel Habrdová, Vilma Pelouch, Radek
http://linked.open...ain/vavai/riv/wos	000285919100018
http://linked.open...n/vavai/riv/zamer	Invasive Approaches to Rescue and Regenerate Jeopardized Myocardium Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	0916-9636
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.1038/hr.2010.183
is http://linked.open...avai/riv/vysledek of	Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy

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