About: Topographical alterations of inner retinal activity during systemic hyperoxia-hypercapnia in normal subjects and patients with type 1 diabetes     Goto   Sponge   NotDistinct   Permalink

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  • The purpose of this study was to investigate whether an increase in the circulating oxygen supply can alter inner retinal function, assessed by recordings of multifocal oscillatory potentials. We studied 9 subjects with type 1 diabetes (8 without overt retinopathy, one with 2 microaneurysms) and 10 similar-aged normal subjects. The central 60 of the retina was stimulated by an array of 61 hexagonal elements, and mfOP recordings were obtained while breathing room air or carbogen. This study demonstrates that some aspects of inner retinal function are modified by the inhalation of carbogen. The reduced effect of carbogen inhalation on the recordings from the patients with diabetes may be due to compromised vascular perfusion in these subjects.
  • The purpose of this study was to investigate whether an increase in the circulating oxygen supply can alter inner retinal function, assessed by recordings of multifocal oscillatory potentials. We studied 9 subjects with type 1 diabetes (8 without overt retinopathy, one with 2 microaneurysms) and 10 similar-aged normal subjects. The central 60 of the retina was stimulated by an array of 61 hexagonal elements, and mfOP recordings were obtained while breathing room air or carbogen. This study demonstrates that some aspects of inner retinal function are modified by the inhalation of carbogen. The reduced effect of carbogen inhalation on the recordings from the patients with diabetes may be due to compromised vascular perfusion in these subjects. (en)
Title
  • Topographical alterations of inner retinal activity during systemic hyperoxia-hypercapnia in normal subjects and patients with type 1 diabetes
  • Topographical alterations of inner retinal activity during systemic hyperoxia-hypercapnia in normal subjects and patients with type 1 diabetes (en)
skos:prefLabel
  • Topographical alterations of inner retinal activity during systemic hyperoxia-hypercapnia in normal subjects and patients with type 1 diabetes
  • Topographical alterations of inner retinal activity during systemic hyperoxia-hypercapnia in normal subjects and patients with type 1 diabetes (en)
skos:notation
  • RIV/00179906:_____/10:10080146!RIV11-MZ0-00179906
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
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  • 3
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  • 293054
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  • RIV/00179906:_____/10:10080146
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  • retina function; oxygen; carbogen; inner retina; Multifocal electroretinography (en)
http://linked.open.../riv/klicoveSlovo
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  • NL - Nizozemsko
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  • [AA3C2BDDAF5B]
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  • Documenta Ophthalmologica
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  • 120
http://linked.open...iv/tvurceVysledku
  • Langrová, Hana
  • Kurtenbach, Anne
  • Dietrich, Traugott
  • Zrener, Eberhart
http://linked.open...ain/vavai/riv/wos
  • 000277638400004
issn
  • 0012-4486
number of pages
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