About: Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma

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About: Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Low-grade cribriform cystadenocarcinoma (LGCCA) of salivary glands is recently described rare tumor with favourable prognosis. We report case of 50-year-old female with swelling lasting for 9 months in right parotideomasseteric area. Grossly, the tumor was well circumscribed and dominated by cystic space. Microscopically, the neoplasm consisted of well demarcated islets, some of them cystically dilated. The architecture of islets varied from solid to cribriform and micropapillary without comedo-type necroses. The tumor cells featured no cytologic atypia. Immunohistochemically, luminal cells showed expression of cytokeratins (CK), CK7, CK18 and S100. Immunostains for CK5/6, CK14, p63 protein and smooth muscle actin displayed continuous rim of myoepithelial cells around all tumor nests. Detection of CK20, hormonal receptors (androgen, estrogen and progesterone), EGFR and Her-2/neu oncoprotein was negative. The patient is free of disease for 2 years. Low-grade cribriform cystadenocarcinoma (LGCCA) of salivary glands is recently described rare tumor with favourable prognosis. We report case of 50-year-old female with swelling lasting for 9 months in right parotideomasseteric area. Grossly, the tumor was well circumscribed and dominated by cystic space. Microscopically, the neoplasm consisted of well demarcated islets, some of them cystically dilated. The architecture of islets varied from solid to cribriform and micropapillary without comedo-type necroses. The tumor cells featured no cytologic atypia. Immunohistochemically, luminal cells showed expression of cytokeratins (CK), CK7, CK18 and S100. Immunostains for CK5/6, CK14, p63 protein and smooth muscle actin displayed continuous rim of myoepithelial cells around all tumor nests. Detection of CK20, hormonal receptors (androgen, estrogen and progesterone), EGFR and Her-2/neu oncoprotein was negative. The patient is free of disease for 2 years. (en)
Title	Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma (en)
skos:prefLabel	Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma (en)
skos:notation	RIV/00179906:_____/10:10072218!RIV11-MZ0-00179906
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Podhola, Miroslav Laco, Jan Doležalová, Helena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	268984
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/10:10072218
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	salivary duct carcinoma; cystadenocarcinoma; low-grade cribriform cystadenocarcinoma; Salivary gland (en)
http://linked.open.../riv/klicoveSlovo	Salivary gland salivary duct carcinoma cystadenocarcinoma low-grade cribriform cystadenocarcinoma
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[090577C4B4A8]
http://linked.open...i/riv/nazevZdroje	International Journal of Surgical Pathology
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Doležalová, Helena Laco, Jan Podhola, Miroslav
http://linked.open...ain/vavai/riv/wos	000281768300013
http://linked.open...n/vavai/riv/zamer	Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	1066-8969
number of pages	5 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma Low-Grade Cribriform Cystadenocarcinoma of the Parotid Gland: a Neoplasm With Favorable Prognosis, Distinct From Salivary Duct Carcinoma

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