About: Perspective taking abilities in amnestic mild cognitive impairment and Alzheimer's disease     Goto   Sponge   NotDistinct   Permalink

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Description
  • Perspective taking is the ability to imagine what a scene looks like from a different viewpoint, which has been reported to be impaired in Alzheimer's disease (AD). This study compared overhead and first-person view perspective taking abilities in patients with mild cognitive impairment (MCI) and AD. A newly developed Arena Perspective Taking Task (APTT), using an environment of a circular arena, was used to compare 23 AD patients and 38 amnestic MCI patients with 18 healthy controls. The results were contrasted with a published perspective taking test (Standardized Road-Map Test of Direction Sense, RMTDS). The AD group was impaired in both overhead and first-person view APTT versions, but the impairment in the overhead view version applied specifically to women. Patients with aMCI were impaired in the first-person view but not in the overhead view version. Substantial sexual differences were found in the overhead but not in the first-person view APTT version. The RMTDS resembled both APTT versions: patients with aMCI were impaired in this test and also women in both patient groups were less accurate than men. Using the receiver operating characteristic analysis, the highest predictive power for MCI and AD patients diagnosis versus controls was observed for their success rate in the first-person view version. The results suggest distinction between overhead and first-person view perspective taking in the impairment of aMCI patients and the sex differences. The first-person view perspective taking is a potentially important candidate psychological marker for AD.
  • Perspective taking is the ability to imagine what a scene looks like from a different viewpoint, which has been reported to be impaired in Alzheimer's disease (AD). This study compared overhead and first-person view perspective taking abilities in patients with mild cognitive impairment (MCI) and AD. A newly developed Arena Perspective Taking Task (APTT), using an environment of a circular arena, was used to compare 23 AD patients and 38 amnestic MCI patients with 18 healthy controls. The results were contrasted with a published perspective taking test (Standardized Road-Map Test of Direction Sense, RMTDS). The AD group was impaired in both overhead and first-person view APTT versions, but the impairment in the overhead view version applied specifically to women. Patients with aMCI were impaired in the first-person view but not in the overhead view version. Substantial sexual differences were found in the overhead but not in the first-person view APTT version. The RMTDS resembled both APTT versions: patients with aMCI were impaired in this test and also women in both patient groups were less accurate than men. Using the receiver operating characteristic analysis, the highest predictive power for MCI and AD patients diagnosis versus controls was observed for their success rate in the first-person view version. The results suggest distinction between overhead and first-person view perspective taking in the impairment of aMCI patients and the sex differences. The first-person view perspective taking is a potentially important candidate psychological marker for AD. (en)
Title
  • Perspective taking abilities in amnestic mild cognitive impairment and Alzheimer's disease
  • Perspective taking abilities in amnestic mild cognitive impairment and Alzheimer's disease (en)
skos:prefLabel
  • Perspective taking abilities in amnestic mild cognitive impairment and Alzheimer's disease
  • Perspective taking abilities in amnestic mild cognitive impairment and Alzheimer's disease (en)
skos:notation
  • RIV/00159816:_____/15:00061632!RIV15-MSM-00159816
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED1.100/02/0123)
http://linked.open...iv/cisloPeriodika
  • March
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 340
http://linked.open...ai/riv/idVysledku
  • RIV/00159816:_____/15:00061632
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Standardized Road-Map Test of Direction Sense; Spatial transformation; Perspective taking task; Mild cognitive impairment; Alzheimer's disease (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [5024EA83AE8B]
http://linked.open...i/riv/nazevZdroje
  • Behavioural Brain Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 281
http://linked.open...iv/tvurceVysledku
  • Hort, Jakub
  • Laczó, Jan
  • Marková, Hana
  • Andel, Rostislav
  • Vlček, Kamil
http://linked.open...ain/vavai/riv/wos
  • 000349504600028
issn
  • 0166-4328
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.bbr.2014.12.033
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