About: Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking

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About: Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking - Initial Experience Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Diffusion Tensor Imaging (DTI) and fiber tractography are established methods to reconstruct major white matter tracts in the human brain in-vivo. Particularly in the context of neurosurgical procedures, reliable information about the course of fiber bundles is important to minimize postoperative deficits while maximizing the tumor resection volume. Since routinely used deterministic streamline tractography approaches often underestimate the spatial extent of white matter tracts, a novel approach to improve fiber segmentation is presented here, considering clinical time constraints. Therefore, fiber tracking visualization is enhanced with statistical information from multiple tracking applications to determine uncertainty in reconstruction based on clinical DTI data. After initial deterministic fiber tracking and centerline calculation, new seed regions are generated along the result's midline. Tracking is applied to all new seed regions afterwards, varying in number and applied offset. The number of fibers passing each voxel is computed to model different levels of fiber bundle membership. Diffusion Tensor Imaging (DTI) and fiber tractography are established methods to reconstruct major white matter tracts in the human brain in-vivo. Particularly in the context of neurosurgical procedures, reliable information about the course of fiber bundles is important to minimize postoperative deficits while maximizing the tumor resection volume. Since routinely used deterministic streamline tractography approaches often underestimate the spatial extent of white matter tracts, a novel approach to improve fiber segmentation is presented here, considering clinical time constraints. Therefore, fiber tracking visualization is enhanced with statistical information from multiple tracking applications to determine uncertainty in reconstruction based on clinical DTI data. After initial deterministic fiber tracking and centerline calculation, new seed regions are generated along the result's midline. Tracking is applied to all new seed regions afterwards, varying in number and applied offset. The number of fibers passing each voxel is computed to model different levels of fiber bundle membership. (en)
Title	Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking - Initial Experience Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking - Initial Experience (en)
skos:prefLabel	Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking - Initial Experience Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking - Initial Experience (en)
skos:notation	RIV/00159816:_____/13:00060613!RIV14-MSM-00159816
http://linked.open...avai/predkladatel	Fakultní nemocnice u sv. Anny v Brně
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.100/02/0123)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Bauer, Miriam Helen Anna
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice u sv.Anny v Brně
http://linked.open...dnocenehoVysledku	101779
http://linked.open...ai/riv/idVysledku	RIV/00159816:_____/13:00060613
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	framework; tractography; human brain; glioma removal; wild bootstrap; thalamic nuclei; dti segmentation; glioblastoma-multiforme; diffusion tensor mri; neuronal fiber pathways (en)
http://linked.open.../riv/klicoveSlovo	framework tractography diffusion tensor mri dti segmentation glioblastoma-multiforme glioma removal neuronal fiber pathways thalamic nuclei wild bootstrap human brain
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[21D336AB7DB6]
http://linked.open...i/riv/nazevZdroje	PLoS ONE
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	8
http://linked.open...iv/tvurceVysledku	Klein, Jan Bauer, Miriam Helen Anna Kuhnt, Daniela Nimsky, Christopher Barbieri, Sebastiano Becker, Andreas Freisleben, Bernd Hahn, Horst K.
http://linked.open...ain/vavai/riv/wos	000321390200042
issn	1932-6203
number of pages	16 (xsd:int)
http://bibframe.org/vocab/doi	10.1371/journal.pone.0063082

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