About: Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe     Goto   Sponge   NotDistinct   Permalink

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  • Background The current European license for alteplase in acute ischemic stroke excludes from treatment large groups of patients. Nevertheless, in everyday practice, many patients receive off-label thrombolysis at the physician's discretion. Aim Our aim was to evaluate safety and effectiveness of intravenous alteplase in patients not fully adhering to the drug license compared with those treated strictly according to the license in Central and Eastern Europe. Methods We analyzed the data contributed to Safe Implementation of Thrombolysis in Stroke registry from nine countries between February 2003 and February 2010. Statistical analysis included multivariate logistic regression.
  • Background The current European license for alteplase in acute ischemic stroke excludes from treatment large groups of patients. Nevertheless, in everyday practice, many patients receive off-label thrombolysis at the physician's discretion. Aim Our aim was to evaluate safety and effectiveness of intravenous alteplase in patients not fully adhering to the drug license compared with those treated strictly according to the license in Central and Eastern Europe. Methods We analyzed the data contributed to Safe Implementation of Thrombolysis in Stroke registry from nine countries between February 2003 and February 2010. Statistical analysis included multivariate logistic regression. (en)
Title
  • Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe
  • Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe (en)
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  • Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe
  • Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe (en)
skos:notation
  • RIV/00098892:_____/12:#0000647!RIV14-MZ0-00098892
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, R
http://linked.open...iv/cisloPeriodika
  • 8
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 142766
http://linked.open...ai/riv/idVysledku
  • RIV/00098892:_____/12:#0000647
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • ischemic stroke, drug treatment (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [1EE21C8FA4CB]
http://linked.open...i/riv/nazevZdroje
  • International Journal of Stroke
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 7
http://linked.open...iv/tvurceVysledku
  • Šaňák, Daniel
issn
  • 1747-4930
number of pages
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