About: Low-dose acyclovir prophylaxis for bortezomib-induced herpes zoster in multuple myeloma patients

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Description	Low-dose acyclovir prophylaxis for bortezomib-induced herpes zoster in multuple myeloma patients Anotace anglicky: In a cohort of 169 patients with multiple myeloma, treated at our department with bortezomib-based chemotherapy, we assessed the incidence of herpes zoster reactivation in patients with and without low dose acyclovir (200mg once daily) prophylaxis. In 78 patients ( 46%) without any prophylaxis, herpes zoster occured in 21 cases (27%). In 92 patients (54%) with low-dose acyclovir prophylaxis there was only one case of herpes zoster in a patient with skipped medication. Most patients with herpes zoster underwent the reactivation within the first three cycles of the treatment. Low-dose acyclovir in multiple myeloma patients treated with bortezomib creates a sufficient prophylaxis of herpes zoster reactivation. Low-dose acyclovir prophylaxis for bortezomib-induced herpes zoster in multuple myeloma patients Anotace anglicky: In a cohort of 169 patients with multiple myeloma, treated at our department with bortezomib-based chemotherapy, we assessed the incidence of herpes zoster reactivation in patients with and without low dose acyclovir (200mg once daily) prophylaxis. In 78 patients ( 46%) without any prophylaxis, herpes zoster occured in 21 cases (27%). In 92 patients (54%) with low-dose acyclovir prophylaxis there was only one case of herpes zoster in a patient with skipped medication. Most patients with herpes zoster underwent the reactivation within the first three cycles of the treatment. Low-dose acyclovir in multiple myeloma patients treated with bortezomib creates a sufficient prophylaxis of herpes zoster reactivation. (en)
Title	Low-dose acyclovir prophylaxis for bortezomib-induced herpes zoster in multuple myeloma patients Low-dose acyclovir prophylaxis for bortezomib-induced herpes zoster in multuple myeloma patients (en)
skos:prefLabel	Low-dose acyclovir prophylaxis for bortezomib-induced herpes zoster in multuple myeloma patients Low-dose acyclovir prophylaxis for bortezomib-induced herpes zoster in multuple myeloma patients (en)
skos:notation	RIV/00098892:_____/12:#0000263!RIV13-MZ0-00098892
http://linked.open...avai/predkladatel	Fakultní nemocnice Olomouc
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NT12451)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Pika, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Olomouc
http://linked.open...dnocenehoVysledku	147515
http://linked.open...ai/riv/idVysledku	RIV/00098892:_____/12:#0000263
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	multiple myeloma, bortezomib, herpes zoster, acyclovir, prophylaxis (en)
http://linked.open.../riv/klicoveSlovo	bortezomib multiple myeloma prophylaxis acyclovir herpes zoster
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[C5673923248E]
http://linked.open...i/riv/nazevZdroje	British Journal of Haematology
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	The significance of the analysis of the pairs of immunoglobulin heavy/light chains by Hevylite TM in monoclonal gammopathy of undetermined significance and multiple myeloma
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	159
http://linked.open...iv/tvurceVysledku	Pika, Tomáš Minařík, Jiří
issn	0007-1048
number of pages	3 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Low-dose acyclovir prophylaxis for bortezomib-induced herpes zoster in multuple myeloma patients

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