About: The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Aims: The presented study is aimed at the evaluation of correlation of free light chains serum levels - kappa, lambda and their relation (K/L ratio) and serum levels of selected biological markers in a group of patients with multiple myeloma examined at the time of the diagnosis. Methods: 102 patients with multiple myeloma were included in this prospective study. Free light chains serum levels were determined by Freelite TM Binding Site system, for determination of serum levels of selected parameters the following methods were used: REA thymidinekinase (TK), RIA (beta2microglobulin), ICTP, PINP, enzymoimmunoassay (sIL-6R, sVCAM-1, sICAM-1, sOPG) and quantitative enzymatic immunoassay (sHGF, sVEGF, sSyndecan-1 (sSyn-1) a sFas). Results: There was found a correlation in the kappa-group of the dominant kappa chain and serum readings of beta2m (r=0,344, p=0,005), TK (r=0,263, p=0,035), ICTP (r=0,402, p=0,001), PINP (r=0,264, p=0,039), sOPG (r=0,328, p=0,028), sSyn-1 (r=0,255, p=0,046) a sFas (r=0,418, p Aims: The presented study is aimed at the evaluation of correlation of free light chains serum levels - kappa, lambda and their relation (K/L ratio) and serum levels of selected biological markers in a group of patients with multiple myeloma examined at the time of the diagnosis. Methods: 102 patients with multiple myeloma were included in this prospective study. Free light chains serum levels were determined by Freelite TM Binding Site system, for determination of serum levels of selected parameters the following methods were used: REA thymidinekinase (TK), RIA (beta2microglobulin), ICTP, PINP, enzymoimmunoassay (sIL-6R, sVCAM-1, sICAM-1, sOPG) and quantitative enzymatic immunoassay (sHGF, sVEGF, sSyndecan-1 (sSyn-1) a sFas). Results: There was found a correlation in the kappa-group of the dominant kappa chain and serum readings of beta2m (r=0,344, p=0,005), TK (r=0,263, p=0,035), ICTP (r=0,402, p=0,001), PINP (r=0,264, p=0,039), sOPG (r=0,328, p=0,028), sSyn-1 (r=0,255, p=0,046) a sFas (r=0,418, p (en)
Title	The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma (en)
skos:prefLabel	The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma (en)
skos:notation	RIV/00098892:_____/08:#0000358!RIV13-MZ0-00098892
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR9500), Z(MSM6198959205)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Lochman, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Olomouc
http://linked.open...dnocenehoVysledku	361398
http://linked.open...ai/riv/idVysledku	RIV/00098892:_____/08:#0000358
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	multiple myeloma, free light chain serum levels, biological parameters (en)
http://linked.open.../riv/klicoveSlovo	multiple myeloma biological parameters free light chain serum levels
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[CCB05BA2BE6E]
http://linked.open...i/riv/nazevZdroje	Biomedical Papers-Olomouc
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Angiogenesis, plasma cell kinetics, parameters of microenvironments of bone marrow and bone metabolism in monoclonal gammopathy of undetermined significance and initial phases of multiple myeloma
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	152
http://linked.open...iv/tvurceVysledku	Pika, Tomáš Lochman, Pavel
http://linked.open...n/vavai/riv/zamer	Studies of genes and molecular mechanisms involved in regulation of hematopoiesis, their clinical impact and targeted treatment
issn	1213-8118
number of pages	4 (xsd:int)
is http://linked.open...avai/riv/vysledek of	The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software