About: Toxic shock syndrome and persistent immune activation in an HIV-positive patient

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The case of an HIV-positive treatment-naive male with toxic shock syndrome (TSS) is presented herein. The course of TSS was favorable; however, the patient had extremely high plasma levels of MCP-1 and CD38 and HLA-DR expression on CD8+ T cells during the acute illness. Furthermore, the numbers of CD8+ T cells were reduced and CD4+ T cells remained stable during acute illness in comparison to baseline values. MCP-1 and HLA-DR gradually decreased, but they were still elevated after a month, whereas the number of circulating CD8+ T cells increased more than fivefold. CD38 expression remained stable during this period. A further decrease in CD38, HLA-DR and MCP-1 was noted five months after the initiation of antiretroviral therapy. The case of an HIV-positive treatment-naive male with toxic shock syndrome (TSS) is presented herein. The course of TSS was favorable; however, the patient had extremely high plasma levels of MCP-1 and CD38 and HLA-DR expression on CD8+ T cells during the acute illness. Furthermore, the numbers of CD8+ T cells were reduced and CD4+ T cells remained stable during acute illness in comparison to baseline values. MCP-1 and HLA-DR gradually decreased, but they were still elevated after a month, whereas the number of circulating CD8+ T cells increased more than fivefold. CD38 expression remained stable during this period. A further decrease in CD38, HLA-DR and MCP-1 was noted five months after the initiation of antiretroviral therapy. (en)
Title	Toxic shock syndrome and persistent immune activation in an HIV-positive patient Toxic shock syndrome and persistent immune activation in an HIV-positive patient (en)
skos:prefLabel	Toxic shock syndrome and persistent immune activation in an HIV-positive patient Toxic shock syndrome and persistent immune activation in an HIV-positive patient (en)
skos:notation	RIV/00064211:_____/13:#0000225!RIV14-MZ0-00064211
http://linked.open...avai/predkladatel	Fakultní nemocnice s poliklinikou na Bulovce
http://linked.open...avai/riv/aktivita	I S
http://linked.open...avai/riv/aktivity	I, S
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Beran, Ondřej Rozsypal, Hanuš Holub, Michal Davidová, Alžběta Jilich, David Arientová, Simona
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Nemocnice Na Bulovce
http://linked.open...dnocenehoVysledku	111415
http://linked.open...ai/riv/idVysledku	RIV/00064211:_____/13:#0000225
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Combined antiretroviral therapy; CD38; HIV infectionHLA-DR, MCP-1, toxic shock syndrome; HLA-DR; toxic shock syndrome (en)
http://linked.open.../riv/klicoveSlovo	CD38 HLA-DR toxic shock syndrome Combined antiretroviral therapy HIV infectionHLA-DR MCP-1
http://linked.open...odStatuVydavatele	AE - Stát Spojené arabské emiráty
http://linked.open...ontrolniKodProRIV	[16B500EDAFAB]
http://linked.open...i/riv/nazevZdroje	Current HIV research.
http://linked.open...in/vavai/riv/obor	FN
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Beran, Ondřej Holub, Michal Rozsypal, Hanuš Jilich, David Arientová, Simona Davidová, Alžběta
http://linked.open...ain/vavai/riv/wos	000324868700009
issn	1570-162X
number of pages	5 (xsd:int)

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