About: Malignant Wegener's Granulomatosis with Fibrosing Mediastinitis and Vena Cava Superior Syndrome     Goto   Sponge   NotDistinct   Permalink

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Description
  • A 47-year-old man was admitted to hospital for migratory joint pain, fatigue, and cough with bloody sputum and proteinuria with increased serum creatinine level. Diagnosis of Wegener's granulomatosis was established. During follow-up, the vena cava superior syndrome developed. The patient died of respiratory failure after 12 years of follow-up. The autopsy revealed rigid, whitish, 12 mm thick tissue, which embedded and compressed the large vessels upwards from their origin in the heart, thus causing vena cava superior syndrome. This tissue was composed of fibrous material without inflammatory cellulization. We consider this fibrous tissue as a manifestation of fibrosing mediastinitis that may or may not share pathogenesis with Wegener's granulomatosis.
  • A 47-year-old man was admitted to hospital for migratory joint pain, fatigue, and cough with bloody sputum and proteinuria with increased serum creatinine level. Diagnosis of Wegener's granulomatosis was established. During follow-up, the vena cava superior syndrome developed. The patient died of respiratory failure after 12 years of follow-up. The autopsy revealed rigid, whitish, 12 mm thick tissue, which embedded and compressed the large vessels upwards from their origin in the heart, thus causing vena cava superior syndrome. This tissue was composed of fibrous material without inflammatory cellulization. We consider this fibrous tissue as a manifestation of fibrosing mediastinitis that may or may not share pathogenesis with Wegener's granulomatosis. (en)
Title
  • Malignant Wegener's Granulomatosis with Fibrosing Mediastinitis and Vena Cava Superior Syndrome
  • Malignant Wegener's Granulomatosis with Fibrosing Mediastinitis and Vena Cava Superior Syndrome (en)
skos:prefLabel
  • Malignant Wegener's Granulomatosis with Fibrosing Mediastinitis and Vena Cava Superior Syndrome
  • Malignant Wegener's Granulomatosis with Fibrosing Mediastinitis and Vena Cava Superior Syndrome (en)
skos:notation
  • RIV/00064203:_____/12:8062!RIV13-MZ0-00064203
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
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  • I
http://linked.open...iv/cisloPeriodika
  • 2
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  • 147914
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  • RIV/00064203:_____/12:8062
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  • immunosuppression; vena cava superior syndrome; Wegener's granulomatosis; fibrosing mediastinitis; glomerulonephritis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [CDEA840E45E7]
http://linked.open...i/riv/nazevZdroje
  • Renal Failure
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  • 34
http://linked.open...iv/tvurceVysledku
  • Špatenka, Jaroslav
  • Stejskal, Josef
  • Matoušovic, Karel
  • Martinek, V.
  • Chadimová, Mária
http://linked.open...ain/vavai/riv/wos
  • 000299784400019
issn
  • 0886-022X
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