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  • Introduction: Little is known about the prognosis of moderate versus critical carotid stenosis treated by carotid artery stenting (CAS). Material and methods: This was a retrospective analysis of a single-centre registry including 271 consecutive patients (69 +/- 9 years, 87% at high risk for surgery), in whom 308 procedures were performed. The study included both symptomatic (>= 50% carotid artery stenosis) and asymptomatic (>= 70% carotid artery stenosis) patients. The primary endpoint was the rate of adverse events during follow-up (range 1-48 months), defined as all-cause death or stroke. Results: We treated 115 critical and 193 moderate stenoses and implanted 318 stents (56% with closed cell design). Embolic protection systems were used in 296 cases (96%). The technical success rate was 98.2% in the critical stenoses group and 99% in the moderate group (NS). During follow-up, the incidence of the primary endpoint was 12.9% (13 pts) in the critical stenoses group and 14.7% (25 pts) in the moderate stenoses group (estimated 3-year freedom from death/stroke was 0.844 vs. 0.812; log-rank test p = 0.983). Left ventricular ejection fraction < 40%, significant contralateral carotid artery occlusion or stenosis and renal insufficiency were identified as significant predictors of the primary endpoint (p < 0.03). Conclusions: Carotid artery stenting with embolic protection systems in patients at high risk for carotid endarterectomy is safe. Patients with initially moderate and critical stenoses have an identical mid-term prognosis with regard to death and stroke.
  • Introduction: Little is known about the prognosis of moderate versus critical carotid stenosis treated by carotid artery stenting (CAS). Material and methods: This was a retrospective analysis of a single-centre registry including 271 consecutive patients (69 +/- 9 years, 87% at high risk for surgery), in whom 308 procedures were performed. The study included both symptomatic (>= 50% carotid artery stenosis) and asymptomatic (>= 70% carotid artery stenosis) patients. The primary endpoint was the rate of adverse events during follow-up (range 1-48 months), defined as all-cause death or stroke. Results: We treated 115 critical and 193 moderate stenoses and implanted 318 stents (56% with closed cell design). Embolic protection systems were used in 296 cases (96%). The technical success rate was 98.2% in the critical stenoses group and 99% in the moderate group (NS). During follow-up, the incidence of the primary endpoint was 12.9% (13 pts) in the critical stenoses group and 14.7% (25 pts) in the moderate stenoses group (estimated 3-year freedom from death/stroke was 0.844 vs. 0.812; log-rank test p = 0.983). Left ventricular ejection fraction < 40%, significant contralateral carotid artery occlusion or stenosis and renal insufficiency were identified as significant predictors of the primary endpoint (p < 0.03). Conclusions: Carotid artery stenting with embolic protection systems in patients at high risk for carotid endarterectomy is safe. Patients with initially moderate and critical stenoses have an identical mid-term prognosis with regard to death and stroke. (en)
Title
  • Comparison of mid-term outcomes of carotid artery stenting for moderate versus critical stenosis
  • Comparison of mid-term outcomes of carotid artery stenting for moderate versus critical stenosis (en)
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  • Comparison of mid-term outcomes of carotid artery stenting for moderate versus critical stenosis
  • Comparison of mid-term outcomes of carotid artery stenting for moderate versus critical stenosis (en)
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  • RIV/00064203:_____/12:7984!RIV13-MZ0-00064203
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 127972
http://linked.open...ai/riv/idVysledku
  • RIV/00064203:_____/12:7984
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • carotid stenosis; stenting; follow-up; endarterectomy; protection; safety; trial (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • PL - Polská republika
http://linked.open...ontrolniKodProRIV
  • [676380AD1B05]
http://linked.open...i/riv/nazevZdroje
  • Archives of Medical Science
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 8
http://linked.open...iv/tvurceVysledku
  • Hájek, Petr
  • Malý, Martin
  • Martinkovičová, Lucia
  • Tomašov, Pavol
  • Veselka, Josef
  • Zemánek, David
  • Zimolová, Petra
  • Špaček, Miloslav
  • Tesař, David
http://linked.open...ain/vavai/riv/wos
  • 000301553600016
issn
  • 1734-1922
number of pages
is http://linked.open...avai/riv/vysledek of
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