About: Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant

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About: Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://casereports.bmj.com/content/2011/bcr.02.2011.3910.abstract
Description	Diffuse cutaneous mastocytosis (DCM) is a rare, severe, variant of cutaneous mastocytosis. The authors report the case of a male infant who developed maculae and maculopapulae on his legs and abdomen when aged 3.5 months, which spread to all body surfaces within weeks. Diagnosis of DCM was made at the age of 6 months when he had developed extensive bullous eruptions, generalised pruritus, flushing and abdominal pain. Treatment was started with oral dimethindine maleate. At the age of 18 months, oral sodium cromoglicate (SCG) was introduced. At the age of 23 months, additional treatment was started with a cutaneous emulsion containing 4% SCG. Continued treatment with oral dimethindine maleate, oral SCG with the dose maintained at 25 mg/kg/day, and SCG 4% cutaneous emulsion applied two to four times daily has resulted in a steady improvement of symptoms and skin appearance. Diffuse cutaneous mastocytosis (DCM) is a rare, severe, variant of cutaneous mastocytosis. The authors report the case of a male infant who developed maculae and maculopapulae on his legs and abdomen when aged 3.5 months, which spread to all body surfaces within weeks. Diagnosis of DCM was made at the age of 6 months when he had developed extensive bullous eruptions, generalised pruritus, flushing and abdominal pain. Treatment was started with oral dimethindine maleate. At the age of 18 months, oral sodium cromoglicate (SCG) was introduced. At the age of 23 months, additional treatment was started with a cutaneous emulsion containing 4% SCG. Continued treatment with oral dimethindine maleate, oral SCG with the dose maintained at 25 mg/kg/day, and SCG 4% cutaneous emulsion applied two to four times daily has resulted in a steady improvement of symptoms and skin appearance. (en)
Title	Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant (en)
skos:prefLabel	Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant (en)
skos:notation	RIV/00064203:_____/11:7254!RIV12-MZ0-00064203
http://linked.open...avai/predkladatel	Fakultní nemocnice v Motole
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	2011
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Čapková, Štěpánka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	218827
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/11:7254
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	altoderm; cetirizine; cromoglycate disodium; desloratadine; dimetindene; ketotifen; levocetirizine; prednisone; tryptase; unclassified drug; abdominal pain; article; blister; bullous skin disease; case report; child; conjunctivitis; diarrhea; differential diagnosis; diffuse cutaneous mastocytosis; disease severity; dose response; drug dose increase; drug dose reduction; emulsion; face edema; flushing; human; infant; maculopapular rash; maintenance drug dose; male; peripheral edema; priority journal; side effect; skin pruritus; skin redness; unspecified side effect; urticaria; urticaria pigmentosa; vomiting (en)
http://linked.open.../riv/klicoveSlovo	emulsion priority journal altoderm bullous skin disease cetirizine conjunctivitis cromoglycate disodium desloratadine diffuse cutaneous mastocytosis dimetindene dose response drug dose increase drug dose reduction face edema flushing ketotifen levocetirizine maculopapular rash maintenance drug dose peripheral edema prednisone side effect skin pruritus skin redness tryptase unclassified drug unspecified side effect urticaria urticaria pigmentosa vomiting human abdominal pain differential diagnosis disease severity case report child - threat - divorce - domestic violence - abandonment - adoption article blister male diarrhea infant
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[5CDA1D7BE604]
http://linked.open...i/riv/nazevZdroje	BMJ Case Reports
http://linked.open...in/vavai/riv/obor	FO
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	2011
http://linked.open...iv/tvurceVysledku	Čapková, Štěpánka Edwards, A. M.
issn	1757-790X
number of pages	5 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant Oral and topical sodium cromoglicate in the treatment of diffuse cutaneous mastocytosis in an infant

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