About: Lung Transplantation in Cystic Fibrosis Patients in the Czech Republic: Initial Single-Center Experience

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Lung transplantation (LuTx) is a well established treatment for advanced lung diseases. We compared the clinical results of patients with cystic fibrosis (CF) entered into the waiting list (WL) with those of patients after LuTx. Among 36 patients with CF on the WL, 23 underwent LuTx, 8 died, 3 are still on WL, and 2 were excluded from WL. The median WL time of 0.48 years (range, 0.03-2.37) was insignificantly longer for patients who died compared with transplanted patients (0.97 vs 0.44 years). Mortality of WL patients was 25.8%. The median survival of transplant patients of 7.48 years (range 0.00-10.85 years) was significantly lower among patients who were colonized with Burkholderia cepacia complex (BCC) versus those who were not colonized (0.19 vs 7.48 years; P = .041). The 1-, 3-, and 5-year patient survivals after LuTx were 72.9, 54.4, and 54.4, respectively. The results of patients with CF on WL versus after LuTx in our center were similar to those reported in the literature. Lung transplantation (LuTx) is a well established treatment for advanced lung diseases. We compared the clinical results of patients with cystic fibrosis (CF) entered into the waiting list (WL) with those of patients after LuTx. Among 36 patients with CF on the WL, 23 underwent LuTx, 8 died, 3 are still on WL, and 2 were excluded from WL. The median WL time of 0.48 years (range, 0.03-2.37) was insignificantly longer for patients who died compared with transplanted patients (0.97 vs 0.44 years). Mortality of WL patients was 25.8%. The median survival of transplant patients of 7.48 years (range 0.00-10.85 years) was significantly lower among patients who were colonized with Burkholderia cepacia complex (BCC) versus those who were not colonized (0.19 vs 7.48 years; P = .041). The 1-, 3-, and 5-year patient survivals after LuTx were 72.9, 54.4, and 54.4, respectively. The results of patients with CF on WL versus after LuTx in our center were similar to those reported in the literature. (en)
Title	Lung Transplantation in Cystic Fibrosis Patients in the Czech Republic: Initial Single-Center Experience Lung Transplantation in Cystic Fibrosis Patients in the Czech Republic: Initial Single-Center Experience (en)
skos:prefLabel	Lung Transplantation in Cystic Fibrosis Patients in the Czech Republic: Initial Single-Center Experience Lung Transplantation in Cystic Fibrosis Patients in the Czech Republic: Initial Single-Center Experience (en)
skos:notation	RIV/00064203:_____/10:6411!RIV11-MZ0-00064203
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MZ0FNM2005)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Lischke, Robert Šimonek, Jan Fila, Libor Burkert, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	269041
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/10:6411
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cystická fibróza; Burkholderia cepacia; čekací listina; plicní transplantace (en)
http://linked.open.../riv/klicoveSlovo	Burkholderia cepacia cystická fibróza čekací listina plicní transplantace
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[ACE4BC55B8F2]
http://linked.open...i/riv/nazevZdroje	Transplantation Proceedings
http://linked.open...in/vavai/riv/obor	FJ
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	42
http://linked.open...iv/tvurceVysledku	Lischke, Robert Šimonek, Jan Adámek, S. Fila, Libor Malý, M. Burkert, Jan Pozniak, J. Valentová Bartáková, L.
http://linked.open...ain/vavai/riv/wos	000284969800067
http://linked.open...n/vavai/riv/zamer	Zdokonalení časné diagnostiky, prevence a léčby těžkých vrozených vývojových vad a chorob geneticky podmíněných či s genetickou dispozicí v prenatální a postnatální fázi vývoje
issn	0041-1345
number of pages	3 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Lung Transplantation in Cystic Fibrosis Patients in the Czech Republic: Initial Single-Center Experience Lung Transplantation in Cystic Fibrosis Patients in the Czech Republic: Initial Single-Center Experience Lung Transplantation in Cystic Fibrosis Patients in the Czech Republic: Initial Single-Center Experience

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