About: Occult thyroid carcinoma

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.ncbi.nlm.nih.gov/pubmed/20463833
Description	Some medical definitions remain the same for many years, others change due to the progress in the diagnostic tools, which are able to distinguish markers and symptoms until then undetectable. Occult thyroid carcinoma is a general term indicating clinically different situations, whereas the incidentally detected papillary thyroid microcarcinoma is the most important from the clinical point of view. It is fundamental, for therapeutic management, to determine biological parameters which would define a small group of papillary thyroid microcarcinomas with aggressive biological behaviour. The most promising genetic and molecular markers for papillary thyroid carcinoma risk stratification are discussed in this review. Preoperative evaluation of these markers, obtained through analysis of ultrasonography-guided fine needle biopsy specimens of papillary thyroid microcarcinoma, could be very valuable in guiding treatment of this type of cancer. Some medical definitions remain the same for many years, others change due to the progress in the diagnostic tools, which are able to distinguish markers and symptoms until then undetectable. Occult thyroid carcinoma is a general term indicating clinically different situations, whereas the incidentally detected papillary thyroid microcarcinoma is the most important from the clinical point of view. It is fundamental, for therapeutic management, to determine biological parameters which would define a small group of papillary thyroid microcarcinomas with aggressive biological behaviour. The most promising genetic and molecular markers for papillary thyroid carcinoma risk stratification are discussed in this review. Preoperative evaluation of these markers, obtained through analysis of ultrasonography-guided fine needle biopsy specimens of papillary thyroid microcarcinoma, could be very valuable in guiding treatment of this type of cancer. (en)
Title	Occult thyroid carcinoma Occult thyroid carcinoma (en)
skos:prefLabel	Occult thyroid carcinoma Occult thyroid carcinoma (en)
skos:notation	RIV/00064203:_____/09:6913!RIV12-MZ0-00064203
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(2B06106)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Betka, Jan Skřivan, Jiří Bouček, Jan Kastner, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	330792
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/09:6913
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Thyroid; Occult carcinoma; Papillary microcarcinoma; Molecular markers; Therapeutic strategy (en)
http://linked.open.../riv/klicoveSlovo	Occult carcinoma Papillary microcarcinoma Therapeutic strategy Thyroid Molecular markers
http://linked.open...odStatuVydavatele	IT - Italská republika
http://linked.open...ontrolniKodProRIV	[55F30D1C648B]
http://linked.open...i/riv/nazevZdroje	Acta Otorhinolaryngologica Italica
http://linked.open...in/vavai/riv/obor	FF
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Novel genomic and biotechlological approaches in molecular oncology: a way to the early diagnostics and targeted therapy
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	29
http://linked.open...iv/tvurceVysledku	Kastner, Jan Betka, Jan Bouček, Jan Skřivan, Jiří Gibelli, B. Giugliano, B. Grosso, E.
http://linked.open...ain/vavai/riv/wos	000277555600003
issn	0392-100X
number of pages	9 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Occult thyroid carcinoma Occult thyroid carcinoma

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