About: Strict Blood-Pressure Control and Progression of Renal Failure in Children

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The blood-pressure target for optimal renal protection is controversial. After a 6-month run-in period, 385 children, 3 to 18 years of age, with glomerular filtration rate of 15 to 80 ml per minute per 1.73 m(2) of BSA received ramipril at a dose of 6 mg per square meter of BSA per day. Patients were randomly assigned to intensified blood-pressure control (with a target 24-hour mean arterial pressure below the 50th percentile) or conventional blood-pressure control (mean arterial pressure in the 50th to 95th percentile), achieved by the addition of antihypertensive therapy; patients were followed for 5 years. Intensified blood-pressure control, with target 24-hour blood-pressure levels in the low range of normal, confers a substantial benefit with respect to renal function among children with chronic kidney disease. The blood-pressure target for optimal renal protection is controversial. After a 6-month run-in period, 385 children, 3 to 18 years of age, with glomerular filtration rate of 15 to 80 ml per minute per 1.73 m(2) of BSA received ramipril at a dose of 6 mg per square meter of BSA per day. Patients were randomly assigned to intensified blood-pressure control (with a target 24-hour mean arterial pressure below the 50th percentile) or conventional blood-pressure control (mean arterial pressure in the 50th to 95th percentile), achieved by the addition of antihypertensive therapy; patients were followed for 5 years. Intensified blood-pressure control, with target 24-hour blood-pressure levels in the low range of normal, confers a substantial benefit with respect to renal function among children with chronic kidney disease. (en)
Title	Strict Blood-Pressure Control and Progression of Renal Failure in Children Strict Blood-Pressure Control and Progression of Renal Failure in Children (en)
skos:prefLabel	Strict Blood-Pressure Control and Progression of Renal Failure in Children Strict Blood-Pressure Control and Progression of Renal Failure in Children (en)
skos:notation	RIV/00064203:_____/09:5336!RIV10-MZ0-00064203
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	17
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Dušek, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice v Motole
http://linked.open...dnocenehoVysledku	344080
http://linked.open...ai/riv/idVysledku	RIV/00064203:_____/09:5336
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	converting-enzyme inhibitor; randomized controlled-trial; glomerular-filtration-rate; kidney-disease; follow-up; ramipril; insufficiency; proteinuria; hypertension; nephropathy (en)
http://linked.open.../riv/klicoveSlovo	ramipril insufficiency follow-up hypertension - ischaemic heart disease - cardiac failure - vitamin D randomized controlled-trial kidney-disease nephropathy converting-enzyme inhibitor proteinuria glomerular-filtration-rate
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[F8086B685355]
http://linked.open...i/riv/nazevZdroje	New England Journal of Medicine
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	35 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	361
http://linked.open...iv/tvurceVysledku	Dušek, Jiří Zurowska, Aleksandra Fischbach, Michel Jankauskiene, Augustina Testa, Sara Anarat, Ali Caliskan, Salim Drozdz, Dorota Emre, Sevinc Gellermann, Jutta Mir, Sevgi Schaefer, Franz Wuehl, Elke Bakkaloglu, Aysin Litwin, Mieczyslaw Jeck, Nikola Peco-Antic, Amira Peruzzi, Licia Arbeiter, Klaus Berg, Ulla Caldas-Afonso, Alberto Enke, Barbara Hohenfellner, Katharina Mehls, Otto Moeller, Kristina Montini, Giovanni Neuhaus, Thomas Niaudet, Patrick Picca, Stefano Sallay, Peter Trivelli, Antonella Urasinski, Tomasz Wigger, Marianne Wingen, Ann-Margret Wygoda, Simone
http://linked.open...ain/vavai/riv/wos	000270977400006
issn	0028-4793
number of pages	12 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Strict Blood-Pressure Control and Progression of Renal Failure in Children Strict Blood-Pressure Control and Progression of Renal Failure in Children Strict Blood-Pressure Control and Progression of Renal Failure in Children Strict Blood-Pressure Control and Progression of Renal Failure in Children

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