About: Riociguat for the treatment of chronic thromboembolic pulmonary hypertension     Goto   Sponge   NotDistinct   Permalink

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Description
  • Riociguat, a memberof a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension.In this phase 3, multicentre, randomized, double-blind, placebo-controlled study, we randomly assigned 261 patients with inoperable chronic thromboembolic pulmonary hypertension or persistent or recurrent pulmonary hypertension after pulmonary endarterectomy to receive placebo or riociguat.
  • Riociguat, a memberof a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension.In this phase 3, multicentre, randomized, double-blind, placebo-controlled study, we randomly assigned 261 patients with inoperable chronic thromboembolic pulmonary hypertension or persistent or recurrent pulmonary hypertension after pulmonary endarterectomy to receive placebo or riociguat. (en)
Title
  • Riociguat for the treatment of chronic thromboembolic pulmonary hypertension
  • Riociguat for the treatment of chronic thromboembolic pulmonary hypertension (en)
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  • Riociguat for the treatment of chronic thromboembolic pulmonary hypertension
  • Riociguat for the treatment of chronic thromboembolic pulmonary hypertension (en)
skos:notation
  • RIV/00064165:_____/13:10195003!RIV14-MZ0-00064165
http://linked.open...avai/predkladatel
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  • 102972
http://linked.open...ai/riv/idVysledku
  • RIV/00064165:_____/13:10195003
http://linked.open...riv/jazykVysledku
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  • endarterectomy; riociguat; chronic thromboembolic pulmonary hypertension (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [DCBD029CBE81]
http://linked.open...i/riv/nazevZdroje
  • New England Journal of Medicine
http://linked.open...in/vavai/riv/obor
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http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
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  • 369
http://linked.open...iv/tvurceVysledku
  • Jansa, Pavel
  • Mayer, Eckhard
  • Kim, Nick H.
  • Simonneau, Gerald
  • Ghofrani, Hossein-Ardeschir
  • D'Armini, Andrea M.
  • Fritsch, Arno
  • Grimminger, Friedrich
  • Hoeper, Marius M.
  • Neuser, Dieter
  • Wang, Chen
  • Weimann, Gerrit
  • Wilkins, Martin R.
http://linked.open...ain/vavai/riv/wos
  • 000322223900007
issn
  • 0028-4793
number of pages
http://bibframe.org/vocab/doi
  • 10.1056/NEJMoa1209657
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