About: Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The ability of two avian P. multocida serogroup F strains to induce disease in rabbits was investigated. Two groups of 18 Pasteurella-free rabbits each were intranasally challenged with strains isolated from chickens and turkeys respectively. Half of the animals in each challenge group were immunosuppressed using dexamethasone. All the challenged rabbits exhibited clinical signs of peracute septicaemic disease, ending with shock, and died or were euthanased in the terminal stages of the disease 1-2 days post-infection. Gross pathological changes included systemic vascular collapse and vascular leak syndrome. Hyperaemia, haemorrhage, oedema, inflammatory cell infiltrates, focal necrosis and degenerative changes were observed histologically in parenchymatous organs. This is the first study directly demonstrating that avian P. multocida serogroup F strains are highly virulent in rabbits and that avian hosts cannot be excluded as a possible source of rabbit infection with serogroup F. The ability of two avian P. multocida serogroup F strains to induce disease in rabbits was investigated. Two groups of 18 Pasteurella-free rabbits each were intranasally challenged with strains isolated from chickens and turkeys respectively. Half of the animals in each challenge group were immunosuppressed using dexamethasone. All the challenged rabbits exhibited clinical signs of peracute septicaemic disease, ending with shock, and died or were euthanased in the terminal stages of the disease 1-2 days post-infection. Gross pathological changes included systemic vascular collapse and vascular leak syndrome. Hyperaemia, haemorrhage, oedema, inflammatory cell infiltrates, focal necrosis and degenerative changes were observed histologically in parenchymatous organs. This is the first study directly demonstrating that avian P. multocida serogroup F strains are highly virulent in rabbits and that avian hosts cannot be excluded as a possible source of rabbit infection with serogroup F. (en)
Title	Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera (en)
skos:prefLabel	Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera (en)
skos:notation	RIV/00027162:_____/11:#0000745!RIV12-MZE-00027162
http://linked.open...avai/predkladatel	Výzkumný ústav veterinárního lékařství, v.v.i,
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ED0006/01/01), P(GA524/05/2714), Z(MZE0002716202)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Jaglič, Zoran Faldyna, Martin Jeklová, Edita Kučerová, Zdeňka Nedbalcová, Kateřina Mašková, Jarmila Levá, Lenka Kummer, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	202752
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/11:#0000745
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pasteurella multocida; virulence; rabbit; chicken; turkey; avian; epidemiology; challenge; infection (en)
http://linked.open.../riv/klicoveSlovo	challenge epidemiology infection virulence chicken rabbit Pasteurella multocida avian turkey
http://linked.open...odStatuVydavatele	CA - Kanada
http://linked.open...ontrolniKodProRIV	[266EFB9A3B51]
http://linked.open...i/riv/nazevZdroje	Canadian Journal of Veterinary Research-REVUE CANADIENNE DE RECHERCHE VETERINAIRE
http://linked.open...in/vavai/riv/obor	FN
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Advanced Microbiology & Immunology Research in Veterinary Medicine Infection of rabbits with Pasteurella multocida serogroups A and F
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	75
http://linked.open...iv/tvurceVysledku	Faldyna, Martin Jaglič, Zoran Kučerová, Zdeňka Levá, Lenka Nedbalcová, Kateřina Jeklová, Edita Christensen, H. Kummer, Vladimír Mašková, Jarmila Register, K.
http://linked.open...ain/vavai/riv/wos	000299528000006
http://linked.open...n/vavai/riv/zamer	Animal disease research, prevention and food chain protection
issn	0830-9000
number of pages	9 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera

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