About: Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The purpose of the study was to analyse frequency of aneuploidies of sex chromosomes and chromosome 6 by three-colour FISH in 47 young fertile bulls and to investigate the influence of aneuploidies and disturbed sperm chromatin integrity on non-return rates, the frequencies of abortions, perinatal mortality and stillbirths. Significant correlation was found between sex disomy, total aneuploidy (disomy of chromosomes 6, X, Y and XY sperm and diploidy) and stillbirths (r=0.390; P=0.013; and r=0.331; P=0.037), non-return rate and total aneuploidy (r=-0.310; P=0.036). Chromosome 6 disomy correlated with perinatal mortality (r=0.317; P=0.047). HDS correlated significantly with total aneuploidy (r=0.449; P=0.002). Our study indicated that aneuploidy frequencies in young fertile bull sperm are relatively low. Nevertheless, there exists a variability in aneuploidy frequencies amongst bulls, which appears to be able to have an influence on the fertility of these animals. The purpose of the study was to analyse frequency of aneuploidies of sex chromosomes and chromosome 6 by three-colour FISH in 47 young fertile bulls and to investigate the influence of aneuploidies and disturbed sperm chromatin integrity on non-return rates, the frequencies of abortions, perinatal mortality and stillbirths. Significant correlation was found between sex disomy, total aneuploidy (disomy of chromosomes 6, X, Y and XY sperm and diploidy) and stillbirths (r=0.390; P=0.013; and r=0.331; P=0.037), non-return rate and total aneuploidy (r=-0.310; P=0.036). Chromosome 6 disomy correlated with perinatal mortality (r=0.317; P=0.047). HDS correlated significantly with total aneuploidy (r=0.449; P=0.002). Our study indicated that aneuploidy frequencies in young fertile bull sperm are relatively low. Nevertheless, there exists a variability in aneuploidy frequencies amongst bulls, which appears to be able to have an influence on the fertility of these animals. (en)
Title	Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility (en)
skos:prefLabel	Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility (en)
skos:notation	RIV/00027162:_____/10:#0000606!RIV11-GA0-00027162
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(1B44018), P(GP523/07/P077)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Rubeš, Jiří Kubíčková, Svatava Rybář, Roman Přinosilová, Petra Kopecká, Věra Věžník, Zdeněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	259018
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/10:#0000606
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	sperm; aneuploidy; bull; FISH; chromatin integrity; meiosis; infertility (en)
http://linked.open.../riv/klicoveSlovo	aneuploidy FISH bull infertility sperm chromatin integrity meiosis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[5AE2369C7B3A]
http://linked.open...i/riv/nazevZdroje	International Journal of Andrology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	The new prediction methods of bull fertility improving the breeding in cattle Chromosomal disorders and chromatin integrity in bull sperm
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	33
http://linked.open...iv/tvurceVysledku	Kubíčková, Svatava Rubeš, Jiří Přinosilová, Petra Rybář, Roman Kopecká, Věra Věžník, Zdeněk
http://linked.open...ain/vavai/riv/wos	000279669200007
issn	0105-6263
number of pages	10 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility

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