About: Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Damage to the genetic component of sperm seems to play the main role in the majority of cases where current approaches fail to reveal the specific cause of male infertility. In the present study, we compared semen quality in men assigned to two defined groups: men from couples with unexplained infertility - idiopathic infertility (A) and young men with no experiences of infertility (B). All samples were examined by standard ejaculate analysis and Sperm chromatin Structure Assay (SCSA). Sperm chromatin damage was significantly higher in men from group A in comparison with men from group B. Similar results were obtained by comparison of men from group A (all men were normozoospermic) and normozoospermic men from groups B. According to these results, we can suppose that chromatin disorders may be the causal factor of subfertility or infertility in some of these men. SCSA is a method which facilitates the identification of infertile men who otherwise show normal semen variables. Damage to the genetic component of sperm seems to play the main role in the majority of cases where current approaches fail to reveal the specific cause of male infertility. In the present study, we compared semen quality in men assigned to two defined groups: men from couples with unexplained infertility - idiopathic infertility (A) and young men with no experiences of infertility (B). All samples were examined by standard ejaculate analysis and Sperm chromatin Structure Assay (SCSA). Sperm chromatin damage was significantly higher in men from group A in comparison with men from group B. Similar results were obtained by comparison of men from group A (all men were normozoospermic) and normozoospermic men from groups B. According to these results, we can suppose that chromatin disorders may be the causal factor of subfertility or infertility in some of these men. SCSA is a method which facilitates the identification of infertile men who otherwise show normal semen variables. (en)
Title	Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples (en)
skos:prefLabel	Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples (en)
skos:notation	RIV/00027162:_____/09:#0000506!RIV10-AV0-00027162
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(1QS500390506)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Faldíková, Ludmila Rubeš, Jiří Rybář, Roman Kopecká, Věra Věžník, Zdeněk Zajícová, Atanáska Kunetková, Monika
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	342936
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/09:#0000506
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA fragmentation; infertility; semen quality; smoking; sperm chromatin structure assay (en)
http://linked.open.../riv/klicoveSlovo	DNA fragmentation semen quality sperm chromatin structure assay infertility smoking - drinking alcohol - students of the University of South Bohemia - preventive programmes
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[BCB2DBEEAD47]
http://linked.open...i/riv/nazevZdroje	Andrologia
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Impact of environmental and genetic factors on men fertility
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	41
http://linked.open...iv/tvurceVysledku	Rubeš, Jiří Rybář, Roman Kopecká, Věra Věžník, Zdeněk Zajícová, Atanáska Marková, P. Kunetková, Monika Faldíková, Ludmila
http://linked.open...ain/vavai/riv/wos	000265480700002
issn	0303-4569
number of pages	10 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples Sperm chromatin integrity in young men with no experiences of infertility and men from idiopathic infertility couples

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