About: Assessment of anticryptosporidial activity of halofuginone-lactate in spontaneously infected calves: a centralized, randomized, double-blind, placebo-controlled study     Goto   Sponge   NotDistinct   Permalink

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  • The preventive administration of halofuginone-lactate (HFL) to newborn calves did not have a greater effect then the treatment of 1-week old animals. Newborn animals were well protected by HFL shortly after treatment, but after withdrawal of drug, they started to shed oocysts, finally shedding fecal scores significantly higher than the group receiving drug therapeutically. Biochemical and haematological parameters remained unaffected suggesting that the treatment with 100 micrograms HFL.kg-1 of body weight for 1 week is safe.
  • The preventive administration of halofuginone-lactate (HFL) to newborn calves did not have a greater effect then the treatment of 1-week old animals. Newborn animals were well protected by HFL shortly after treatment, but after withdrawal of drug, they started to shed oocysts, finally shedding fecal scores significantly higher than the group receiving drug therapeutically. Biochemical and haematological parameters remained unaffected suggesting that the treatment with 100 micrograms HFL.kg-1 of body weight for 1 week is safe. (en)
  • Preventivní podávání halofuginon-laktátu (HFL) novorozeným telatům nemělo větší účinek než léčebné podávání u týden starých zvířat. Novorozená telata byla pomocí HFL dobře chráněna během léčby a bezprostředně po ní, ale po vysazení léku začala vylučovat oocysty, přičemž nakonec byl počet oocyst v jejich výkalech větší než u skupiny, kterým byl HFL podáván terapeuticky. Biochemické a hematologické ukazatele se neměnily, z čehož lze usoudit, že dávka 100 mikrogramů HFL na kg živé hmotnosti je bezpečná. (cs)
Title
  • Assessment of anticryptosporidial activity of halofuginone-lactate in spontaneously infected calves: a centralized, randomized, double-blind, placebo-controlled study
  • Assessment of anticryptosporidial activity of halofuginone-lactate in spontaneously infected calves: a centralized, randomized, double-blind, placebo-controlled study (en)
  • Ověření aktivity halofuginon laktátu proti kryptosporidiím u spontánně infikovaných telat: centralizovaná, randomizovaná, dvojitě zaslepená, placebem kontrolovaná klinická studie (cs)
skos:prefLabel
  • Assessment of anticryptosporidial activity of halofuginone-lactate in spontaneously infected calves: a centralized, randomized, double-blind, placebo-controlled study
  • Assessment of anticryptosporidial activity of halofuginone-lactate in spontaneously infected calves: a centralized, randomized, double-blind, placebo-controlled study (en)
  • Ověření aktivity halofuginon laktátu proti kryptosporidiím u spontánně infikovaných telat: centralizovaná, randomizovaná, dvojitě zaslepená, placebem kontrolovaná klinická studie (cs)
skos:notation
  • RIV/00027014:_____/06:#0000323!RIV07-MZE-00027014
http://linked.open.../vavai/riv/strany
  • 85
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MZE0002701403)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 466136
http://linked.open...ai/riv/idVysledku
  • RIV/00027014:_____/06:#0000323
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • calves, Cryptosporidium parvum, diarrhea, halofuginone-lactate (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [128AC98A8696]
http://linked.open...v/mistoKonaniAkce
  • Turin, Italy
http://linked.open...i/riv/mistoVydani
  • Garsington
http://linked.open...i/riv/nazevZdroje
  • Proceedings of the 10th International Congress of The European Association for Veterinary Pharmacology nad Toxicology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Klein, Pavel
  • Skřivanová, Věra
  • Kudrna, Václav
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
issn
  • 0140-7783
number of pages
http://purl.org/ne...btex#hasPublisher
  • Blackwell Publishing
is http://linked.open...avai/riv/vysledek of
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