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  • Distribuce mitochondrií v rekonstruovaných myších oocytech. Byla hodnocena distribuce mitochondrií v rekonstruovaných nezralých oocytech myši, kde značený karyoplast (GV) byl fúzován s neznačeným cytoplastem. Po fúzi došlo k rovnoměrnému rozptýlení mitochondrií v cytoplazmě. Rychlost distribuce je však závislá na stádiu buněčného cyklu. (cs)
  • We have examined the pattern of DNA methylation in human embryos. In about half of the zygotes the paternal chromatin was less methylated than the maternal chromatin. In the other half, both pronuclei exhibited the same intensity of labeling. High levels of labeling were observed for up to four cell stage, thereafter the decline of labeling was detected. Remethylation in some nuclei starts in late morulae. In the blastocyst, the inner cell mass showed a weaker intensity of labeling than the trophectoderm.
  • We have examined the pattern of DNA methylation in human embryos. In about half of the zygotes the paternal chromatin was less methylated than the maternal chromatin. In the other half, both pronuclei exhibited the same intensity of labeling. High levels of labeling were observed for up to four cell stage, thereafter the decline of labeling was detected. Remethylation in some nuclei starts in late morulae. In the blastocyst, the inner cell mass showed a weaker intensity of labeling than the trophectoderm. (en)
Title
  • DNA methylation pattern in human zygotes and developing embryos
  • DNA methylation pattern in human zygotes and developing embryos (en)
  • Úroveň methylace DNA v lidských zygotách a embryích (cs)
skos:prefLabel
  • DNA methylation pattern in human zygotes and developing embryos
  • DNA methylation pattern in human zygotes and developing embryos (en)
  • Úroveň methylace DNA v lidských zygotách a embryích (cs)
skos:notation
  • RIV/00027014:_____/04:00010976!RIV/2005/GA0/M02005/N
http://linked.open.../vavai/riv/strany
  • 703-708
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA524/02/0032)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
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http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 560967
http://linked.open...ai/riv/idVysledku
  • RIV/00027014:_____/04:00010976
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http://linked.open.../riv/klicovaSlova
  • embryo;DNA;epigenetics (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [140A6624309E]
http://linked.open...i/riv/nazevZdroje
  • Reproduction
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http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 128
http://linked.open...iv/tvurceVysledku
  • Fulka jr., Josef
  • Fulková, Helena
issn
  • 1470-1626
number of pages
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