About: In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro.

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Nízkomolekulární inhbitor akarbóza inhubuje in vitro amylázu skladištního roztoče Acarus siro. Tato inhibice se in vivo projeví blokováním využití škrobu jako potravního zdroje pro tento druh roztoče. Takto ovlivnění roztoči se pomaleji množí, rychlost jejich populačního růstu závisí na koncentraci použitého inhibitoru. (cs) Novel acaricidal compounds with inhibitory effects on the digestive enzymes of arthropods are a safe alternative to the traditional neurotoxic pesticides used for control of the stored-product pests. In this work, we explored the properties of acarbose, the low molecular weight inhibitor of -amylases (AI), as a novel acaricide candidate for protection of the stored products from infestation by Acarus siro (Acari: Acaridae). In vitro analysis revealed that AI blocked efficiently the enzymatic activity of digestive amylases of A. siro, and decreased the physiological capacity of mites gut in utilizing a starch component of grain flour. In vivo experiments showed that AI suppressed the population growth of A. siro. The mites were kept for three weeks on experimental diet enriched by AI in concentration range of 0.005 to 0.25%. Population growth of A. siro was negatively correlated with the content of AI in the treated diet with a half-population dose of 0.125%. The suppressive effect of AIs on stored-pr Novel acaricidal compounds with inhibitory effects on the digestive enzymes of arthropods are a safe alternative to the traditional neurotoxic pesticides used for control of the stored-product pests. In this work, we explored the properties of acarbose, the low molecular weight inhibitor of -amylases (AI), as a novel acaricide candidate for protection of the stored products from infestation by Acarus siro (Acari: Acaridae). In vitro analysis revealed that AI blocked efficiently the enzymatic activity of digestive amylases of A. siro, and decreased the physiological capacity of mites gut in utilizing a starch component of grain flour. In vivo experiments showed that AI suppressed the population growth of A. siro. The mites were kept for three weeks on experimental diet enriched by AI in concentration range of 0.005 to 0.25%. Population growth of A. siro was negatively correlated with the content of AI in the treated diet with a half-population dose of 0.125%. The suppressive effect of AIs on stored-pr (en)
Title	In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro. In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro. (en) In vitro a in vivo inhibice amylázy skladištního roztoče Acarus siro. (cs)
skos:prefLabel	In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro. In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro. (en) In vitro a in vivo inhibice amylázy skladištního roztoče Acarus siro. (cs)
skos:notation	RIV/00027006:_____/05:2845!RIV08-MZE-00027006
http://linked.open.../vavai/riv/strany	281;291
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(OC 842.20), Z(MZE0002700603)
http://linked.open...iv/cisloPeriodika	0
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Křížková Kudlíková, Iva Stejskal, Václav Hubert, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav rostlinné výroby, v.v.i.
http://linked.open...dnocenehoVysledku	524472
http://linked.open...ai/riv/idVysledku	RIV/00027006:_____/05:2845
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	amylase; Acarus siro; Inhibitor; Stored-product mite (en)
http://linked.open.../riv/klicoveSlovo	Inhibitor amylase Acarus siro Stored-product mite
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[5DFB4AC68B13]
http://linked.open...i/riv/nazevZdroje	Experimental and Applied Acarology
http://linked.open...in/vavai/riv/obor	GF
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/OC%20842.20
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	35
http://linked.open...iv/tvurceVysledku	Hubert, Jan Stejskal, Václav Mareš, M. Křížková Kudlíková, Iva Dolečková, L. Hýblová, J.
http://linked.open...n/vavai/riv/zamer	Environment friendly systems of plant and stored product protection against harmful organisms aimed at quality and health safety plant products
issn	0168-8162
number of pages	11 (xsd:int)
is http://linked.open...avai/riv/vysledek of	In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro.

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