About: Neuroanatomical abnormalities as risk factors for bipolar disorder

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Článek na základě neurozobrazovacích studií nepostižených příbuzných bipolárních pacientů, pediatrické bipolární poruchy, pacientů s první epizodou a pacientů s rodinnou anamnézou bipolární poruchy pátrá po neuroanatomických změnách použitelných jako biologické markery pro bipolární poruchy. (cs) OBJECTIVE: Neuroimaging studies show structural brain abnormalities in bipolar patients. Some of the abnormalities may represent biological risk factors conveying vulnerability for the disease. This paper aims to identify neuroanatomical risk factors for bipolar disorder (BD). METHODS: We reviewed magnetic resonance imaging (MRI) findings in populations in which the effects of the disease or treatment are minimal or where the chances of finding genetically coded risk factors shared within the families are increased. Such populations include unaffected relatives of bipolar patients, first-episode patients, children or adolescents with BD and patients with familial BD. RESULTS: MEDLINE search revealed 30 relevant scientific papers. Abnormalities in the volume of the striatum, left hemispheric white matter, thalamus and anterior cingulate as well as quantitative MRI signal hyperintensities were identified already in unaffected relatives of bipolar patients. Subjects in the early stages of the disease sho OBJECTIVE: Neuroimaging studies show structural brain abnormalities in bipolar patients. Some of the abnormalities may represent biological risk factors conveying vulnerability for the disease. This paper aims to identify neuroanatomical risk factors for bipolar disorder (BD). METHODS: We reviewed magnetic resonance imaging (MRI) findings in populations in which the effects of the disease or treatment are minimal or where the chances of finding genetically coded risk factors shared within the families are increased. Such populations include unaffected relatives of bipolar patients, first-episode patients, children or adolescents with BD and patients with familial BD. RESULTS: MEDLINE search revealed 30 relevant scientific papers. Abnormalities in the volume of the striatum, left hemispheric white matter, thalamus and anterior cingulate as well as quantitative MRI signal hyperintensities were identified already in unaffected relatives of bipolar patients. Subjects in the early stages of the disease sho (en)
Title	Neuroanatomical abnormalities as risk factors for bipolar disorder Neuroanatomical abnormalities as risk factors for bipolar disorder (en) Neuroanatomické změny jako rizikové faktory bipolární poruchy (cs)
skos:prefLabel	Neuroanatomical abnormalities as risk factors for bipolar disorder Neuroanatomical abnormalities as risk factors for bipolar disorder (en) Neuroanatomické změny jako rizikové faktory bipolární poruchy (cs)
skos:notation	RIV/00023752:_____/05:00000883!RIV09-MZ0-00023752
http://linked.open...avai/riv/aktivita	N S
http://linked.open...avai/riv/aktivity	N, S
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Hájek, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Národní ústav duševního zdraví
http://linked.open...dnocenehoVysledku	532562
http://linked.open...ai/riv/idVysledku	RIV/00023752:_____/05:00000883
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adolescents; amygdala; bipolar disorder; children; hippocampus; magnetic resonance imaging; striatum; subgenual prefrontal cortes (en)
http://linked.open.../riv/klicoveSlovo	hippocampus amygdala children magnetic resonance imaging adolescents striatum bipolar disorder subgenual prefrontal cortes
http://linked.open...odStatuVydavatele	DK - Dánské království
http://linked.open...ontrolniKodProRIV	[A9FB5D2F1A79]
http://linked.open...i/riv/nazevZdroje	Bipolar Disorders
http://linked.open...in/vavai/riv/obor	FL
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	7
http://linked.open...iv/tvurceVysledku	Hájek, Tomáš Alda, M. Carrey, N.
issn	1398-5647
number of pages	11 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Neuroanatomical abnormalities as risk factors for bipolar disorder

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