About: Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report)

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About: Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report) Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Objective: This paper presents functional magnetic resonance imaging (fMRI) and magnetic resonance spectroscopy (MRS) findings in a monozygotic twin pair discordant for schizophrenia. Method: Functional magnetic resonance imaging was used to determine hemispheric lateralization for speech and proton MRS (1H-MRS) was employed to assess the extent of putative insult to anterior hippocampus. Results: Despite concordant right handedness, subject with schizophrenia displayed bilateral activation in areas subserving speech with greater extent of the total activated area compared with the healthy twin. The affected twin displayed relative bilateral decrease in N-acetylaspartate/creatin concentration in the anterior hippocampus compared with the healthy one. Conclusion: This is an evidence for non-genetic impairment of cerebral lateralization in monozygotic twin with schizophrenia. Objective: This paper presents functional magnetic resonance imaging (fMRI) and magnetic resonance spectroscopy (MRS) findings in a monozygotic twin pair discordant for schizophrenia. Method: Functional magnetic resonance imaging was used to determine hemispheric lateralization for speech and proton MRS (1H-MRS) was employed to assess the extent of putative insult to anterior hippocampus. Results: Despite concordant right handedness, subject with schizophrenia displayed bilateral activation in areas subserving speech with greater extent of the total activated area compared with the healthy twin. The affected twin displayed relative bilateral decrease in N-acetylaspartate/creatin concentration in the anterior hippocampus compared with the healthy one. Conclusion: This is an evidence for non-genetic impairment of cerebral lateralization in monozygotic twin with schizophrenia. (en)
Title	Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report) Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report) (en)
skos:prefLabel	Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report) Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report) (en)
skos:notation	RIV/00023752:_____/03:00000320!RIV/2004/MZ0/L28004/N
http://linked.open.../vavai/riv/strany	155-158
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NF6794)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Hájek, Tomáš Španiel, Filip
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Národní ústav duševního zdraví
http://linked.open...dnocenehoVysledku	603826
http://linked.open...ai/riv/idVysledku	RIV/00023752:_____/03:00000320
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	schizophrenia; twins; monozygotic; functional magnetic resonance imaging; magnetic resonance spectroscopy (en)
http://linked.open.../riv/klicoveSlovo	magnetic resonance spectroscopy schizophrenia twins functional magnetic resonance imaging monozygotic
http://linked.open...odStatuVydavatele	DK - Dánské království
http://linked.open...ontrolniKodProRIV	[692240A40F0D]
http://linked.open...i/riv/nazevZdroje	Acta Psychiatrica Scandinavica
http://linked.open...in/vavai/riv/obor	FL
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Hippocampal impairment in schizophrenia: proton magnetic resonance spectroscopy study and dermatoglyphic analysis
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	107
http://linked.open...iv/tvurceVysledku	Hájek, Tomáš Hájek, Milan Španiel, Filip Dezortová, Monika Tintěra, Jaroslav Harantová, Pavlína
issn	0001-690X
number of pages	4 (xsd:int)

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