About: Brain maldevelopment and neurobehavioural deviations in adult rats treated neonatally with indomethacin

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About: Brain maldevelopment and neurobehavioural deviations in adult rats treated neonatally with indomethacin Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Model experiments in rats simulating perinatal use of indomethacin in high-risk neonates have shown that the pattern of behavioural (motor aktivity, emotional reactivity, pain sensitivity) and neuroendocrine (pituitary function, brain monoamine transmission) deviations in adult animals was highly dependent on the ontogenic phase exposed to drug insult. Model experiments in rats simulating perinatal use of indomethacin in high-risk neonates have shown that the pattern of behavioural (motor aktivity, emotional reactivity, pain sensitivity) and neuroendocrine (pituitary function, brain monoamine transmission) deviations in adult animals was highly dependent on the ontogenic phase exposed to drug insult. (en)
Title	Brain maldevelopment and neurobehavioural deviations in adult rats treated neonatally with indomethacin Brain maldevelopment and neurobehavioural deviations in adult rats treated neonatally with indomethacin (en)
skos:prefLabel	Brain maldevelopment and neurobehavioural deviations in adult rats treated neonatally with indomethacin Brain maldevelopment and neurobehavioural deviations in adult rats treated neonatally with indomethacin (en)
skos:notation	RIV/00023752:_____/01:00000067!RIV/2002/MZ0/L28002/N
http://linked.open.../vavai/riv/strany	367-373
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(IZ4014), P(IZ4291), P(NF6031)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2002
http://linked.open...aciTvurceVysledku	Benešová, Olga Krištofiková, Zdena Tejkalová, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Národní ústav duševního zdraví
http://linked.open...dnocenehoVysledku	674670
http://linked.open...ai/riv/idVysledku	RIV/00023752:_____/01:00000067
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Brain maldevelopment, Perinatal pharmacotherapy, Indomethacin, Behavioural teratogenicity, Nociception, Neuroendocrine defects (en)
http://linked.open.../riv/klicoveSlovo	Indomethacin Nociception Behavioural teratogenicity Brain maldevelopment Neuroendocrine defects Perinatal pharmacotherapy
http://linked.open...odStatuVydavatele	IE - Irsko
http://linked.open...ontrolniKodProRIV	[B9CB6DD6585F]
http://linked.open...i/riv/nazevZdroje	European Neuropsychopharmacology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Risk of persistent neuro-immuno-behavioural deviations induced by perinatal administration of indomethacine. The risk of hypothalamo-pituitary-thyroid axis maldevelopment as a consequence of perinatal glucocorticoid and indomethacine administration. Role of glutamatergic system in neurodevelopmental animal model of schizophrenia.
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Hušek, Petr Yamamotová, Anna Krištofiková, Zdena Tejkalová, Hana Benešová, Olga Nedvídková, Jaroslava
issn	0924-977X
number of pages	7 (xsd:int)

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