About: TP53 codon 72 polymorphism and cervical cancer : a pooled analysis of individual data from 49 studies     Goto   Sponge   NotDistinct   Permalink

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  • Cervical cancer is caused primarily by human papillomaviruses (HPV). The polymorphism rs1042522 at codon 72 of the TP53 tumour-suppressor gene has been investigated as a genetic cofactor. More than 80 studies were done between 1998 and 2006, after it was initially reported that women who are homozygous for the arginine allele had a risk for cervical cancer seven times higher than women who were heterozygous for the allele. However, results have been inconsistent. Here we analyse pooled data from 49 studies to determine whether there is an association between TP53 codon 72 polymorphism and cervical cancer.
  • Cervical cancer is caused primarily by human papillomaviruses (HPV). The polymorphism rs1042522 at codon 72 of the TP53 tumour-suppressor gene has been investigated as a genetic cofactor. More than 80 studies were done between 1998 and 2006, after it was initially reported that women who are homozygous for the arginine allele had a risk for cervical cancer seven times higher than women who were heterozygous for the allele. However, results have been inconsistent. Here we analyse pooled data from 49 studies to determine whether there is an association between TP53 codon 72 polymorphism and cervical cancer. (en)
Title
  • TP53 codon 72 polymorphism and cervical cancer : a pooled analysis of individual data from 49 studies
  • TP53 codon 72 polymorphism and cervical cancer : a pooled analysis of individual data from 49 studies (en)
skos:prefLabel
  • TP53 codon 72 polymorphism and cervical cancer : a pooled analysis of individual data from 49 studies
  • TP53 codon 72 polymorphism and cervical cancer : a pooled analysis of individual data from 49 studies (en)
skos:notation
  • RIV/00023736:_____/09:00008273!RIV10-MZ0-00023736
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 8
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 346608
http://linked.open...ai/riv/idVysledku
  • RIV/00023736:_____/09:00008273
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cervical cancer; p53; polymorphism (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [F6536ABFCC59]
http://linked.open...i/riv/nazevZdroje
  • Lancet oncology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 10
http://linked.open...iv/tvurceVysledku
  • Tachezy, Ruth
  • Koenig, M.
  • Klug, S. J.
  • von Knebel-Doeberitz, M.
  • Abba, M. C.
  • Agorastos, T.
  • Blettner, M.
  • Brenna, S. M.
  • Ciotti, M.
  • Das, B. R.
  • Del Mistro, A.
  • Dybikowska, A.
  • Giuliano, A. R.
  • Gudleviciene, Z.
  • Gyllesten, U.
  • Haws, A. L.
  • Helland, A.
  • Herrington, C. S.
  • Hildesheim, A.
  • Humbey, O.
  • Jee, S. H.
  • Kim, J. W.
  • Madeleine, M. M.
  • Menczer, J.
  • Ngan, H. Y.
  • Nishikawa, A.
  • Niwa, Y.
  • Pegoraro, R.
  • Pillai, M. R.
  • Ranzani, G.
  • Ressing, M.
  • Rezza, G.
  • Rosenthal, A. N.
  • Roychoudhury, S.
  • Saranath, D.
  • Schmitt, M. V.
  • Sengupta, S.
  • Settheetham-Ishida, W.
  • Shirasawa, H.
  • Snijders, P. J.
  • Stoler, M. H.
  • Suárez-Rincón, A. E.
  • Szarka, K.
  • Ueda, M.
  • Wu, M.-T.
  • Yamashita, T.
  • Zehbe, I.
  • van der Zee, A. G.
http://linked.open...ain/vavai/riv/wos
  • 000268697700016
issn
  • 1470-2045
number of pages
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