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  • We confirmed reactivation of telomerase activity in hematopoietic stem cells of MDS patients, all having shortened telomeres. Our findings suggest a possibility to use dynamics of telomerase activity as a marker of MDS. Nevertheless, determination of telomere length seems to be more effective in stratification of patients in risk of progression of MDS and conversion of MDS towards overt of leukemia.
  • We confirmed reactivation of telomerase activity in hematopoietic stem cells of MDS patients, all having shortened telomeres. Our findings suggest a possibility to use dynamics of telomerase activity as a marker of MDS. Nevertheless, determination of telomere length seems to be more effective in stratification of patients in risk of progression of MDS and conversion of MDS towards overt of leukemia. (en)
Title
  • Telomerase activity as a prospective molecular marker of myelodysplastic syndromes.
  • Telomerase activity as a prospective molecular marker of myelodysplastic syndromes. (en)
skos:prefLabel
  • Telomerase activity as a prospective molecular marker of myelodysplastic syndromes.
  • Telomerase activity as a prospective molecular marker of myelodysplastic syndromes. (en)
skos:notation
  • RIV/00023736:_____/03:00000081!RIV/2004/MZ0/L33004/N
http://linked.open.../vavai/riv/strany
  • S63;S64
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NC5903), Z(MZ00237360001)
http://linked.open...iv/cisloPeriodika
  • S1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...dnocenehoVysledku
  • 630440
http://linked.open...ai/riv/idVysledku
  • RIV/00023736:_____/03:00000081
http://linked.open...riv/jazykVysledku
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  • telomerase activity; myelodysplastic syndromes; disease prognosis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [260A7E92F826]
http://linked.open...i/riv/nazevZdroje
  • Leukemia Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
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http://linked.open...v/svazekPeriodika
  • 27
http://linked.open...iv/tvurceVysledku
  • Čermák, Jaroslav
  • Starý, J.
  • Říhová, Hana
  • Březinová, Dagmar
  • Sieglová, Zuzana
  • Žilovcová, Soňa
http://linked.open...n/vavai/riv/zamer
issn
  • 0145-2126
number of pages
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