About: The effects of photodynamic treatment on chronic myelogenous leukemia cell line K562.     Goto   Sponge   NotDistinct   Permalink

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  • The cytotoxic effects of photodynamic therapy (PDT) on K562 cells were studied. Using bromodeoxyuridine or 3H-thymidine incorporation methods the suppression of proliferation by 40 -50 % was found. By immunoblotting using specific antibodies the processes were revealed suggesting initiation of apoptosis: release of cytochrome c from mitochondria into cytoplasm and suppression of anti-apoptotic protein Bcl-XL after PDT.
  • The cytotoxic effects of photodynamic therapy (PDT) on K562 cells were studied. Using bromodeoxyuridine or 3H-thymidine incorporation methods the suppression of proliferation by 40 -50 % was found. By immunoblotting using specific antibodies the processes were revealed suggesting initiation of apoptosis: release of cytochrome c from mitochondria into cytoplasm and suppression of anti-apoptotic protein Bcl-XL after PDT. (en)
Title
  • The effects of photodynamic treatment on chronic myelogenous leukemia cell line K562.
  • The effects of photodynamic treatment on chronic myelogenous leukemia cell line K562. (en)
skos:prefLabel
  • The effects of photodynamic treatment on chronic myelogenous leukemia cell line K562.
  • The effects of photodynamic treatment on chronic myelogenous leukemia cell line K562. (en)
skos:notation
  • RIV/00023736:_____/02:00000151!RIV/2003/MZ0/L33003/N
http://linked.open.../vavai/riv/strany
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  • P(GA301/01/0200), P(NC5883), Z(MZ00237360001)
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  • 644444
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  • RIV/00023736:_____/02:00000151
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  • K562 cells; photodynamic treatment; proliferation; cytochrome c; Bcl-XL (en)
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  • [8612F5D69929]
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  • Praha
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  • Praha
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  • Conference of post-graduate students, ICT.
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  • Hrkal, Zbyněk
  • Pluskalová, Michaela
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http://linked.open...n/vavai/riv/zamer
number of pages
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  • Vysoká škola chemicko-technologická v Praze
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