About: Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis

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About: Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In bone biopsies in 29 patients in the teriparatide group and 22 in the SrR group, the mineralization surfaces as a percent of bone surfaces (MS/BS, %) at the endocortical level measured after 6 mo of treatment were 17.22 +/- 3.06% and 9.70 +/- 2.07%, respectively (p = 0.052). The changes in biochemical markers of bone formation confirmed bone-forming activity of teriparatide but not of SrR treatment. The effects of SrR on bone remodeling and cell activity were modest, indicating that its effects on fracture reduction may be predominantly mediated through a different mechanism than that observed with anabolic or more potent antiresorptive agents. In bone biopsies in 29 patients in the teriparatide group and 22 in the SrR group, the mineralization surfaces as a percent of bone surfaces (MS/BS, %) at the endocortical level measured after 6 mo of treatment were 17.22 +/- 3.06% and 9.70 +/- 2.07%, respectively (p = 0.052). The changes in biochemical markers of bone formation confirmed bone-forming activity of teriparatide but not of SrR treatment. The effects of SrR on bone remodeling and cell activity were modest, indicating that its effects on fracture reduction may be predominantly mediated through a different mechanism than that observed with anabolic or more potent antiresorptive agents. (en)
Title	Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis (en)
skos:prefLabel	Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis (en)
skos:notation	RIV/00023728:_____/09:00000098!RIV10-MZ0-00023728
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Štěpán, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Revmatologický ústav
http://linked.open...dnocenehoVysledku	307642
http://linked.open...ai/riv/idVysledku	RIV/00023728:_____/09:00000098
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Biological Markers; Bone Remodeling; Osteoporosis; Strontium ranelate; Teriparatide (en)
http://linked.open.../riv/klicoveSlovo	Biological Markers Bone Remodeling Strontium ranelate Osteoporosis Teriparatide
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[3DA482392C55]
http://linked.open...i/riv/nazevZdroje	Journal of Bone and Mineral Research
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Štěpán, Jan Marin, F. Recker, R. R. Farrerons, J. Hawkins, F. Ish-Shalom, S. Kapetanos, G. Kekow, J. Möricke, R. Oertel, H. Sanz, B. de la Pena, G. P.
http://linked.open...ain/vavai/riv/wos	000268861300003
issn	0884-0431
number of pages	11 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis

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