About: Twin valve caval stent for functional replacement of incompetent tricuspid valve: a feasibility animal study

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To evaluate feasibility of a twin valve caval stent (TVCS) for functional replacement of an incompetent tricuspid valve (TV) in an acute animal study. One swine and three sheep were used in the study. TVCS placement was tested in a swine with a normal TV. TVCS function was tested in three sheep with TV regurgitation created by papillary muscle avulsion. Cardiac angiograms and pressure measurements were used to evaluate TVCS function. Two sheep were studied after fluid overload. TVCS was percutaneously placed properly at the central portions of the superior vena cava (SVC) and inferior vena cava (IVC) in the swine. Papillary muscle avulsion in three sheep caused significant tricuspid regurgitation with massive reflux into the right atrium (RA) and partial reflux into the SVC and IVC. TVCS placement eliminated reflux into the SVC and IVC. After fluid overload, there was enlargement of the right ventricle and RA and significant increase in right ventricle, RA, SVC, and IVC pressures, but no reflux into the IVC and SVC. The results of this feasibility study justify detailed evaluation of TVCS insertion for functional chronic replacement of incompetent TV. To evaluate feasibility of a twin valve caval stent (TVCS) for functional replacement of an incompetent tricuspid valve (TV) in an acute animal study. One swine and three sheep were used in the study. TVCS placement was tested in a swine with a normal TV. TVCS function was tested in three sheep with TV regurgitation created by papillary muscle avulsion. Cardiac angiograms and pressure measurements were used to evaluate TVCS function. Two sheep were studied after fluid overload. TVCS was percutaneously placed properly at the central portions of the superior vena cava (SVC) and inferior vena cava (IVC) in the swine. Papillary muscle avulsion in three sheep caused significant tricuspid regurgitation with massive reflux into the right atrium (RA) and partial reflux into the SVC and IVC. TVCS placement eliminated reflux into the SVC and IVC. After fluid overload, there was enlargement of the right ventricle and RA and significant increase in right ventricle, RA, SVC, and IVC pressures, but no reflux into the IVC and SVC. The results of this feasibility study justify detailed evaluation of TVCS insertion for functional chronic replacement of incompetent TV. (en)
Title	Twin valve caval stent for functional replacement of incompetent tricuspid valve: a feasibility animal study Twin valve caval stent for functional replacement of incompetent tricuspid valve: a feasibility animal study (en)
skos:prefLabel	Twin valve caval stent for functional replacement of incompetent tricuspid valve: a feasibility animal study Twin valve caval stent for functional replacement of incompetent tricuspid valve: a feasibility animal study (en)
skos:notation	RIV/00023001:_____/11:00002522!RIV12-MZ0-00023001
http://linked.open...avai/predkladatel	Institut klinické a experimentální mediciny
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MZ0IKEM2005)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Peregrin, Jan Šochman, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	236302
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/11:00002522
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Tricuspid regurgitation; Caval valve stent; Animal experiment; Functional tricuspid replacement (en)
http://linked.open.../riv/klicoveSlovo	Animal experiment Caval valve stent Functional tricuspid replacement Tricuspid regurgitation
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[739CAC9D33C5]
http://linked.open...i/riv/nazevZdroje	Cardiovascular and Interventional Radiology
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	34
http://linked.open...iv/tvurceVysledku	Peregrin, Jan Šochman, Jan Choi, Young Ho Keller, Frederick S Pavcnik, Dusan Roesch, Josef Shimohira, Masashi Timmermans, Hans A Uchida, Barry T
http://linked.open...ain/vavai/riv/wos	000286191200025
http://linked.open...n/vavai/riv/zamer	Výzkum kardiovaskulárních nemocí, diabetu a transplantace životně důležitých orgánů
issn	0174-1551
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s00270-010-0039-0
is http://linked.open...avai/riv/vysledek of	Twin valve caval stent for functional replacement of incompetent tricuspid valve: a feasibility animal study Twin valve caval stent for functional replacement of incompetent tricuspid valve: a feasibility animal study

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