About: Sudden cardiac death thirty years ago and at present. The role of autonomic disturbances in acute myocardial infarction revisited

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About: Sudden cardiac death thirty years ago and at present. The role of autonomic disturbances in acute myocardial infarction revisited Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.biomed.cas.cz/physiolres/pdf/60/60_715.pdf
Description	The most common cause of sudden cardiac death is ventricular fibrillation (VF). In addition to the status, size and location of the ventricular focus, a major pathogenic mechanism triggering VF is autonomic dysbalance (disturbance). This term refers to a wide range of reflex changes in the ratio of sympathetic to vagal ventricular activation over time, occurring immediately after coronary artery occlusion at the onset of acute myocardial infarction (AMI). Another trigger of VF is autonomic disturbance due to emotional stress. Experimental and clinical research into autonomic disturbances associated with coronary artery occlusion and emotional stress was given considerable attention as early as some 30 years ago when researchers were already searching for ways of inhibiting autonomic disturbances using predominant sympathetic and vagal activation by beta-blockers (BB) and atropine, respectively. The aim of our paper is to compare results obtained 30 years ago with current status of experimental and clinical research into SCD prevention. Another aim is to identify questions that have remained unanswered to date; answers to these outstanding questions could help further reduce the risk of SCD. The most common cause of sudden cardiac death is ventricular fibrillation (VF). In addition to the status, size and location of the ventricular focus, a major pathogenic mechanism triggering VF is autonomic dysbalance (disturbance). This term refers to a wide range of reflex changes in the ratio of sympathetic to vagal ventricular activation over time, occurring immediately after coronary artery occlusion at the onset of acute myocardial infarction (AMI). Another trigger of VF is autonomic disturbance due to emotional stress. Experimental and clinical research into autonomic disturbances associated with coronary artery occlusion and emotional stress was given considerable attention as early as some 30 years ago when researchers were already searching for ways of inhibiting autonomic disturbances using predominant sympathetic and vagal activation by beta-blockers (BB) and atropine, respectively. The aim of our paper is to compare results obtained 30 years ago with current status of experimental and clinical research into SCD prevention. Another aim is to identify questions that have remained unanswered to date; answers to these outstanding questions could help further reduce the risk of SCD. (en)
Title	Sudden cardiac death thirty years ago and at present. The role of autonomic disturbances in acute myocardial infarction revisited Sudden cardiac death thirty years ago and at present. The role of autonomic disturbances in acute myocardial infarction revisited (en)
skos:prefLabel	Sudden cardiac death thirty years ago and at present. The role of autonomic disturbances in acute myocardial infarction revisited Sudden cardiac death thirty years ago and at present. The role of autonomic disturbances in acute myocardial infarction revisited (en)
skos:notation	RIV/00023001:_____/11:00002520!RIV12-MZ0-00023001
http://linked.open...avai/predkladatel	Institut klinické a experimentální mediciny
http://linked.open...avai/riv/aktivita	I N S
http://linked.open...avai/riv/aktivity	I, N, S
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Staněk, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	233343
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/11:00002520
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Sudden death; Myocardial ischemia; Ventricular fibrillation; Autonomic disturbances; Prevention (en)
http://linked.open.../riv/klicoveSlovo	Autonomic disturbances Myocardial ischemia Sudden death Prevention Ventricular fibrillation
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[23BB614A7B5E]
http://linked.open...i/riv/nazevZdroje	Physiological research
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	60
http://linked.open...iv/tvurceVysledku	Pokorný, J. Staněk, Vladimír Vrána, M.
http://linked.open...ain/vavai/riv/wos	000298159900001
issn	0862-8408
number of pages	14 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Sudden cardiac death thirty years ago and at present. The role of autonomic disturbances in acute myocardial infarction revisited Sudden cardiac death thirty years ago and at present. The role of autonomic disturbances in acute myocardial infarction revisited

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