About: Experience with a naphthylmedetomidine - ketamine - hyaluronidase combination in inducing immobilization in anthropoid apes

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Background: The aim of the study was to compare the effect of naphthylmedetomidine to medetomidine on the behavior of orangutans and chimpanzees. Methods: The immobilization was performed as part of a medical examination in five chimpanzees and three orangutans. Following pre-medication with midazolam (0.70-1.20 mg/kg p.o.), naphthylmedetomidine (50-70 mu g/kg), or medetomidine (20-30 mu g/kg) was given with ketamine (3 mg/kg) and hyaluronidase (150 M.U.) into musculus deltoideus. Results: We observed the distinct anti-aggressive effect of naphthylmedetomidine. The immobilization with naphthylmedetomidine was shallower and the influence on cardiac frequency less substantial compared to medetomidine. The overall sedative effect of naphthylmedetomidine lasted for less time, and its effect was incompletely antagonized with atipamezole in comparison to medetomidine. Conclusions: Naphthylmedetomidine could replace medetomidine for inducing immobilization and sedation. A combination of naphthylmedetomidi Background: The aim of the study was to compare the effect of naphthylmedetomidine to medetomidine on the behavior of orangutans and chimpanzees. Methods: The immobilization was performed as part of a medical examination in five chimpanzees and three orangutans. Following pre-medication with midazolam (0.70-1.20 mg/kg p.o.), naphthylmedetomidine (50-70 mu g/kg), or medetomidine (20-30 mu g/kg) was given with ketamine (3 mg/kg) and hyaluronidase (150 M.U.) into musculus deltoideus. Results: We observed the distinct anti-aggressive effect of naphthylmedetomidine. The immobilization with naphthylmedetomidine was shallower and the influence on cardiac frequency less substantial compared to medetomidine. The overall sedative effect of naphthylmedetomidine lasted for less time, and its effect was incompletely antagonized with atipamezole in comparison to medetomidine. Conclusions: Naphthylmedetomidine could replace medetomidine for inducing immobilization and sedation. A combination of naphthylmedetomidi (en)
Title	Experience with a naphthylmedetomidine - ketamine - hyaluronidase combination in inducing immobilization in anthropoid apes Experience with a naphthylmedetomidine - ketamine - hyaluronidase combination in inducing immobilization in anthropoid apes (en)
skos:prefLabel	Experience with a naphthylmedetomidine - ketamine - hyaluronidase combination in inducing immobilization in anthropoid apes Experience with a naphthylmedetomidine - ketamine - hyaluronidase combination in inducing immobilization in anthropoid apes (en)
skos:notation	RIV/00023001:_____/10:00002387!RIV11-MZ0-00023001
http://linked.open...avai/riv/aktivita	I P V
http://linked.open...avai/riv/aktivity	I, P(NR9168), V
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Hess, Ladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	258217
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/10:00002387
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	chimpanzee; immobilization; medetomidine; naphthylmedetomidine; orangutan (en)
http://linked.open.../riv/klicoveSlovo	orangutan medetomidine chimpanzee naphthylmedetomidine immobilization
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[7816AD5885D0]
http://linked.open...i/riv/nazevZdroje	Journal of medical primatology
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	THE COMBINATION OF ALPHA-2 SYMPATHOMIMETCS, OPIOIDS AND KETAMINE TO IMPROVE PERI-OPERATIVE COURSE
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	39
http://linked.open...iv/tvurceVysledku	Málek, J. Hess, Ladislav Horáček, M. Votava, M. Schreiberová, J.
http://linked.open...ain/vavai/riv/wos	000277415800003
issn	0047-2565
number of pages	9 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Experience with a naphthylmedetomidine - ketamine - hyaluronidase combination in inducing immobilization in anthropoid apes Experience with a naphthylmedetomidine - ketamine - hyaluronidase combination in inducing immobilization in anthropoid apes Experience with a naphthylmedetomidine - ketamine - hyaluronidase combination in inducing immobilization in anthropoid apes

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