About: Association of the -344T/C aldosterone synthase gene variant with essential hypertension

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About: Association of the -344T/C aldosterone synthase gene variant with essential hypertension Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aldosterone synthase gene (CYP11B2) is an important candidate gene region in essential hypertension. We therefore studied the association of -344T/C polymorphism of the CYP11B2 gene with the presence and severity of hypertension in a case-control study. We studied 369 individuals, of whom 213 were hypertensive patients (139 controlled hypertensive, 74 resistant hypertensive) and 156 were healthy normotensive subjects. The -344T/C polymorphism of the CYP11B2 gene was determined using polymerase chain reaction - restriction fragment length polymorphism analysis. The aldosterone synthase gene (CYP11B2) is an important candidate gene region in essential hypertension. We therefore studied the association of -344T/C polymorphism of the CYP11B2 gene with the presence and severity of hypertension in a case-control study. We studied 369 individuals, of whom 213 were hypertensive patients (139 controlled hypertensive, 74 resistant hypertensive) and 156 were healthy normotensive subjects. The -344T/C polymorphism of the CYP11B2 gene was determined using polymerase chain reaction - restriction fragment length polymorphism analysis. (en)
Title	Association of the -344T/C aldosterone synthase gene variant with essential hypertension Association of the -344T/C aldosterone synthase gene variant with essential hypertension (en)
skos:prefLabel	Association of the -344T/C aldosterone synthase gene variant with essential hypertension Association of the -344T/C aldosterone synthase gene variant with essential hypertension (en)
skos:notation	RIV/00023001:_____/09:00002154!RIV10-MZ0-00023001
http://linked.open...avai/riv/aktivita	V Z
http://linked.open...avai/riv/aktivity	V, Z(MZ0FNM2005)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Lánská, Věra
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Institut klinické a experimentální medicíny
http://linked.open...dnocenehoVysledku	304252
http://linked.open...ai/riv/idVysledku	RIV/00023001:_____/09:00002154
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	aldosterone synthase; hypertension; polymorphism; aldosterone (en)
http://linked.open.../riv/klicoveSlovo	aldosterone hypertension - ischaemic heart disease - cardiac failure - vitamin D polymorphism aldosterone synthase
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[5FCBB88E327F]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	58
http://linked.open...iv/tvurceVysledku	Lánská, Věra Linhart, A. Horký, K. Heller, S. Hlubocká, Z. Jáchymová, M. Danzig, V. Umnerová, V.
http://linked.open...ain/vavai/riv/wos	000273296600002
http://linked.open...n/vavai/riv/zamer	Zdokonalení časné diagnostiky, prevence a léčby těžkých vrozených vývojových vad a chorob geneticky podmíněných či s genetickou dispozicí v prenatální a postnatální fázi vývoje
issn	0862-8408
number of pages	8 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Association of the -344T/C aldosterone synthase gene variant with essential hypertension Association of the -344T/C aldosterone synthase gene variant with essential hypertension Association of the -344T/C aldosterone synthase gene variant with essential hypertension Association of the -344T/C aldosterone synthase gene variant with essential hypertension

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